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Related Concept Videos

Overview of Cell Death01:30

Overview of Cell Death

Cell death is an essential process where the body gets rid of old or damaged cells. Cell proliferation and death need to be balanced, as an imbalance between the two may lead to cancer or autoimmune diseases.
Cell death was observed in the early 19th century, but there was no experimental evidence to prove it. In 1842, Carl Vogt first discovered cell death in a metamorphic toad; however, it was not termed ‘cell death.’ Scientists discovered different cell death pathways only in the 20th century...
Kubler Ross's Stages of Dying01:21

Kubler Ross's Stages of Dying

Elisabeth Kübler-Ross significantly advanced psychology's understanding of the process of dying with her influential book, On Death and Dying (1969). She focused on studying terminally ill individuals and outlined five stages commonly experienced when coping with death: denial, anger, bargaining, depression, and acceptance.
In denial, individuals reject the reality of their condition, often thinking, "This isn't true; I feel fine," as a way to protect themselves from emotional distress. Anger...
Autophagic Cell Death01:18

Autophagic Cell Death

Christian de Duve discovered “autophagy,” a process in which cellular components are engulfed by membrane-bound organelles called autophagosomes. The autophagosomes then fuse with lysosomes to digest the enclosed contents. Autophagy is generally activated in cells to prevent cell death. However, cell death is triggered when the damage is beyond repair.
Autophagy and Apoptosis
Autophagy can activate apoptosis. In normal conditions, the autophagy activating protein Beclin-1 and pro-apoptotic...
Necrosis01:16

Necrosis

Necrosis is considered as an “accidental” or unexpected form of cell death that ends in cell lysis. The first noticeable mention of “necrosis” was in 1859 when Rudolf Virchow used this term to describe advanced tissue breakdown in his compilation titled “Cell Pathology”.
Morphological Manifestations of Necrosis
Necrotic cells show different types of morphological appearance depending on the type of tissue and infection. In coagulative necrosis, cells become anucleated and die, but their...
Functions of Life01:23

Functions of Life

Human life is characterized by a variety of functions that are essential for survival and well-being. These functions include metabolism, movement, development, growth and reproduction.
Metabolism
The basic function of an organism is to consume energy and molecules in foods, convert some of it into fuel for movement, sustain body functions, and build and maintain body structures. There are two types of reactions that accomplish this: anabolism and catabolism.
Anabolism is the process whereby...
Life Tables01:22

Life Tables

A life table is a statistical tool that summarizes the mortality and survival patterns of a population, providing detailed insights into the likelihood of survival or death across different age intervals within a cohort. By organizing data on survival probabilities and mortality rates, life tables offer a clear snapshot of population dynamics over time. They are extensively used in demography, public health, actuarial science, and ecology to analyze life expectancy, design health interventions,...

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Updated: Jun 9, 2026

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
07:08

A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death

Published on: June 6, 2025

A death before life.

Elizabeth Lynch

    Nursing Standard (Royal College of Nursing (Great Britain) : 1987)
    |September 2, 2010
    PubMed
    Summary
    This summary is machine-generated.

    New stillbirth guidelines recommend offering parents the option to hold their baby. This compassionate approach supports parental grieving after a stillbirth, acknowledging the importance of bonding.

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    A High-Fidelity Porcine Model of Orthotopic Heart Transplantation Following Donation after Circulatory Death
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    Strategies for Tracking Anastasis, A Cell Survival Phenomenon that Reverses Apoptosis

    Published on: February 16, 2015

    Area of Science:

    • Perinatal Medicine
    • Grief Counseling

    Background:

    • Stillbirth is a significant adverse pregnancy outcome.
    • Parental grief following stillbirth is profound and complex.

    Purpose of the Study:

    • To update clinical guidelines regarding stillbirth care.
    • To incorporate recommendations for parental-infant bonding after stillbirth.

    Main Methods:

    • Review of existing literature and clinical practices.
    • Consensus development among experts in obstetrics and bereavement care.

    Main Results:

    • Updated guidelines now emphasize offering parents the option to hold their stillborn infant.
    • This recommendation aims to facilitate the grieving process and acknowledge the infant's existence.

    Conclusions:

    • Providing the option to hold a stillborn baby is a key component of sensitive perinatal bereavement care.
    • Implementing these guidelines can improve the experience for parents navigating stillbirth.