Intraocular gas associated pressure-induced interface keratopathy 8 years after laser in situ keratomileusis

The authors report a clinically distinctive form of elevated intraocular pressure-induced interface keratopathy that occurred after a pars plana vitrectomy with intraocular gas tamponade for a macular hole in the right eye in a 35-year-old woman who had laser in situ keratomileusis in both eyes 8 years previously. The intraocular pressure was increased to 37 mm Hg after surgery. Diffuse lamellar keratitis-like interface infiltration was found with concurrent elevated intraocular pressure. The interface infiltration did not respond to steroids but resolved after the intraocular pressure was controlled. This case suggests that interface keratopathy is associated with increased intraocular pressure. Assessment of intraocular pressure is essential in patients presenting with interface keratopathy, especially in those who have undergone posterior segment operations with gas tamponade.