Treatment of stasis dermatitis using aminaphtone: a case series

José Maria Pereira de Godoy1

  • 1The Angiology and Vascular Surgery Service of the Medicine School in São José do Rio Preto, FAMERP, Rua Floriano Peixoto 2950, São Paulo, Zip code 15010-020, Brazil. godoyjmp@riopreto.com.br.

Insights

Aminaphtone effectively treated stasis purpura in four patients over one year. The treatment resolved brown patches associated with this vascular condition without new lesions appearing.

Area of Science:

  • Vascular Medicine
  • Dermatology

Background:

  • Stasis purpura is a frequent clinical observation.
  • It is associated with underlying vascular changes.

Purpose of the Study:

  • To evaluate the efficacy of aminaphtone in treating stasis purpura.

Main Methods:

  • A case series of four Caucasian patients with stasis purpura was treated with aminaphtone.
  • Treatment duration was approximately one year.

Main Results:

  • All four patients experienced complete resolution of stasis purpura lesions.
  • No new lesions or adverse effects were reported during the treatment period.

Conclusions:

  • Aminaphtone represents a potential new therapeutic option for stasis purpura.
  • This treatment is particularly relevant when capillary fragility is a contributing factor.
Abstract

Related Concept Videos

Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses, temperature changes,...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...