Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Anchoring-and-Adjustment Heuristic01:25

The Anchoring-and-Adjustment Heuristic

In order to make good decisions, we use our knowledge and our reasoning. Often, this knowledge and reasoning is sound and solid. However, sometimes, we are swayed by biases or by others manipulating a situation. For example, let’s say you and three friends wanted to rent a house and had a combined target budget of $1,600. The realtor shows you only very run-down houses for $1,600 and then shows you a very nice house for $2,000. Might you ask each person to pay more in rent to get the $2,000...
Robbers Cave04:49

Robbers Cave

During the 1950s, the landmark Robbers Cave experiment demonstrated that when groups must compete with one another, intergroup conflict, hostility, and even violence may result. At the Oklahoman summer camp, two troops of boys—termed the Rattlers and the Eagles—took part in a week-long tournament. During this time, their negativity culminated in derogatory name-calling, fistfights, and even vandalism and destruction of property. However, this work also revealed that such tension could be...
Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Uncertainty in Measurement: Reading Instruments02:46

Uncertainty in Measurement: Reading Instruments

Counting is the type of measurement that is free from uncertainty, provided the number of objects being counted does not change during the process. Such measurements result in exact numbers. By counting the eggs in a carton, for instance, one can determine exactly how many eggs are there in the carton. Similarly, the numbers of defined quantities are also exact. For example, 1 foot is exactly 12 inches, 1 inch is exactly 2.54 centimeters, and 1 gram is exactly 0.001 kilograms. Quantities...
Cavity Drainage and Flashings in Masonry walls01:20

Cavity Drainage and Flashings in Masonry walls

Typically, a cavity wall consists of two wythes separated by a gap of at least 2 inches, which may contain insulation while still maintaining a minimum clear space of 1 inch to facilitate adequate drainage. Advanced methods like the insertion of a continuous drainage mat can further reduce this space while ensuring effective moisture expulsion.
Weep holes, strategically placed at the base of the cavity, are critical for draining accumulated water. These openings are created by leaving head...
Law of Independent Assortment02:03

Law of Independent Assortment

While Mendel’s Law of Segregation states that the two alleles for one gene are separated into different gametes, a different question of how different genes are inherited remains. For example, is the gene for tall plants inherited with the gene for green peas? Mendel asked this question by experimenting with a dihybrid cross; a cross in which both parents are homozygous for two distinct traits resulting in an F1 generation that are heterozygous for both traits.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Oncology Medical Homes: ASCO-Community Oncology Alliance Standards.

JCO oncology practice·2025
Same author

Overlooked Risk in Cancer Care: Failure of Medical Reconciliation.

JCO oncology practice·2025
Same author

Supportive Care for Cancer Patients Via Telehealth: Breaking Bad News and Providing Palliative Care Virtually.

Cancer journal (Sudbury, Mass.)·2024
Same author

Physician Disruptive Behavior Compromising Safe Care Delivery.

JCO oncology practice·2024
Same author

Preventing Future Harm: Identifying the Drivers of an Unsafe Discharge to Improve Safety on an Inpatient Oncology Service.

JCO oncology practice·2023
Same author

Telehealth in Oncology: ASCO Standards and Practice Recommendations.

JCO oncology practice·2021

Related Experiment Video

Updated: Jun 9, 2026

Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina
09:05

Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina

Published on: May 6, 2015

Caveat emptor.

Therese M Mulvey1

  • 1Southcoast Center for Cancer Care, Fall River, MA.

Journal of Oncology Practice
|September 3, 2010
PubMed
Summary

Genetic factors significantly influence cancer risk, but the impact of low-penetrance genes remains unclear. Further research is needed to understand these genetic predispositions for better cancer prevention strategies.

Area of Science:

  • Genetics
  • Oncology
  • Cancer Risk Assessment

Background:

  • Genetic mutations are a known factor in cancer development.
  • The role of low-penetrance genes in cancer susceptibility is not fully understood.
  • Accurate risk assessment is crucial for effective cancer prevention.

Purpose of the Study:

  • To highlight the current uncertainty surrounding low-penetrance genes and cancer risk.
  • To emphasize the need for a clearer understanding of genetic contributions to cancer.
  • To inform current risk assessment and counseling practices.

Main Methods:

  • Review of existing literature on cancer genetics and gene penetrance.
  • Analysis of the implications of low-penetrance genes in cancer etiology.

More Related Videos

Blue-hazard-free Candlelight OLED
10:18

Blue-hazard-free Candlelight OLED

Published on: March 19, 2017

Taste Exam: A Brief and Validated Test
07:10

Taste Exam: A Brief and Validated Test

Published on: August 17, 2018

Related Experiment Videos

Last Updated: Jun 9, 2026

Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina
09:05

Imaging Ca2+ Dynamics in Cone Photoreceptor Axon Terminals of the Mouse Retina

Published on: May 6, 2015

Blue-hazard-free Candlelight OLED
10:18

Blue-hazard-free Candlelight OLED

Published on: March 19, 2017

Taste Exam: A Brief and Validated Test
07:10

Taste Exam: A Brief and Validated Test

Published on: August 17, 2018

  • Synthesis of current knowledge gaps in genetic cancer risk.

    • Main Results:

    • The contribution of low-penetrance genes to overall cancer risk is currently difficult to quantify.
    • Existing genetic testing and counseling may not fully account for low-penetrance variants.
    • Significant knowledge gaps exist in understanding the functional impact of these genes.

    Conclusions:

    • A comprehensive understanding of low-penetrance genes is essential for accurate cancer risk prediction.
    • Current advice regarding cancer risk associated with these genes should be cautious.
    • Further research is imperative to elucidate the precise role of low-penetrance genes in cancer development.