Related Experiment Videos
2-Amino-2-oxazolines, III: Synthesis, structure, and preliminary pharmacological evaluation of cycloaddition
1Laboratoire de Chimie Physique, Faculté des Sciences Pharmaceutiques, Université de Bordeaux II, France.
Archiv Der Pharmazie
|November 1, 1990
Abstract:
The reaction of 5-substituted 2-amino-2-oxazolines with unsaturated carboxylic esters yielded 2,3,5,6-tetrahydro- and 2,3-dihydro-7H-oxazolo[3,2-a]pyrimidin-7-ones. The structure of these compounds was established by IR- and NMR-spectra and by X-ray crystallography. They were tested for anti-arrhythmic and hypocholesterolemic activities.