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Updated: Jun 9, 2026
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An Orthotopic Model of Murine Bladder Cancer
Published on: February 6, 2011
Urinary bladder diverticulum and its association with malignancy: an anatomical study on cadavers
Prakash1, T Rajini, Ajay Kumar Bhardwaj
1Department of Anatomy, Vydehi Institute of Medical Sciences and Research Centre, Whitefield, Bangalore, Karnataka, India. prakashrinku@rediffmail.com
Summary
Urinary bladder diverticula are more common than previously thought, with a significant percentage showing malignant changes. Early detection and treatment of bladder diverticula are crucial to prevent cancer development.
Area of Science:
- Urology
- Anatomy
- Pathology
Background:
- Urinary bladder diverticula and their association with malignancy are documented through radiological and endoscopic studies.
- Previous research has highlighted the potential complications of bladder diverticula.
Purpose of the Study:
- To investigate the prevalence and anatomical basis of urinary bladder diverticulum formation.
- To determine the association between urinary bladder diverticula and malignancy using cadaveric dissection.
Main Methods:
- Dissection of 30 embalmed cadavers (19 males, 11 females) of varying ages.
- Examination of the urinary bladder for diverticulum presence, number, and location.
- Review of cadaver death records to identify cases of urinary bladder diverticular carcinoma.
Main Results:
- A prevalence of 23.4% for urinary bladder diverticula was observed (31.6% in males, 9.1% in females).
- Diverticula were consistently located superior and lateral to the ureteric opening on the posterior bladder surface.
- Malignant changes were found in 14.3% of identified urinary bladder diverticula, a higher rate than previously reported.
Conclusions:
- The prevalence of urinary bladder diverticula may be higher than previously estimated.
- A notable percentage of urinary bladder diverticula are associated with malignancy.
- Prompt diagnosis and treatment of urinary bladder diverticula are essential to prevent malignant transformation and improve patient outcomes.
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