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Updated: Jun 9, 2026
08:32
Adapting Human Videofluoroscopic Swallow Study Methods to Detect and Characterize Dysphagia in Murine Disease Models
Published on: March 1, 2015
Rare case of dysphagia.
Bobby R Kakati1, Shyam M Dang, Muhannad M Heif
1Department of Internal Medicine, University of Arkansas for Medical Sciences, 4301 W. Markham Street, Slot#634, Little Rock, AR 72205, USA. bkakati@uams.edu
Dysphagia
|September 3, 2010
Summary
Wound botulism is a rare condition, usually seen in drug users. Early diagnosis and treatment with antitoxin are crucial for preventing severe outcomes like dysphagia and neurological deficits.
Area of Science:
- Medical Microbiology
- Infectious Diseases
- Neurology
Background:
- Wound botulism is a rare neuroparalytic illness caused by Clostridium botulinum toxin.
- It predominantly affects injection drug users, but non-injection-related cases have been reported.
Observation:
- A case of wound botulism in a non-injecting drug user following a motorcycle accident with open fractures.
- The patient presented with dysphagia and neurological deficits, necessitating intensive care and antitoxin therapy.
Findings:
- Delayed diagnosis and treatment led to prolonged dysphagia, requiring a feeding tube and extensive rehabilitation.
- Prompt administration of heptavalent *Clostridium botulinum* antitoxin is critical for effective management.
Implications:
- Highlights the importance of considering wound botulism in patients with dysphagia and diplopia after open wounds, regardless of drug use history.
- Emphasizes that early suspicion and intervention can prevent severe morbidity and mortality associated with this life-threatening condition.
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