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NiO Nanoflowers for Non-Enzymatic Amperometric Detection of Glucose
Published on: December 30, 2025
Electrospun Co3O4 nanofibers for sensitive and selective glucose detection
1Department of Chemical, Materials and Biomolecular Engineering, University of Connecticut, 191 Auditorium Rd, Storrs, CT 06269-3222, USA.
Biosensors & Bioelectronics
|September 3, 2010
Summary
Cobalt oxide (Co3O4) nanofibers were synthesized for a novel non-enzymatic glucose sensor. This sensor demonstrates high sensitivity and selectivity for glucose detection in biological samples.
Area of Science:
- Materials Science
- Electrochemistry
- Nanotechnology
Background:
- Enzyme-free glucose detection is crucial for diabetes management.
- Developing sensitive and selective glucose sensors remains a challenge.
Purpose of the Study:
- To fabricate Co3O4 nanofibers for non-enzymatic glucose sensing.
- To evaluate the performance of the Co3O4 nanofiber-based sensor.
Main Methods:
- Electrospinning and calcination for Co3O4 nanofiber synthesis.
- Electron microscopy (SEM, TEM) for morphology.
- Spectroscopy (FTIR, Raman, XRD, XPS) for characterization.
- Fabrication of a non-enzymatic glucose sensor.
Main Results:
- Successfully synthesized Co3O4 nanofibers with confirmed structure and composition.
- The sensor exhibited a rapid response (<7 s), high sensitivity (36.25 μA mM⁻¹ cm⁻²), and low detection limit (0.97 μM).
- The sensor demonstrated excellent selectivity against interfering substances and stability in high NaCl concentrations, performing well with human blood serum samples.
Conclusions:
- Co3O4 nanofibers are effective materials for developing highly sensitive and selective enzyme-free glucose sensors.
- The proposed sensor shows significant potential for practical applications in glucose monitoring.
