Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Understanding Sleep01:11

Understanding Sleep

Sleep, an essential biological state, involves significant reductions in physical activity, sensory awareness, and interaction with the environment. This complex physiological process is primarily regulated by specific brain regions, notably the hypothalamus and pons, which govern the sleep-wake cycle or circadian rhythm.
The circadian rhythm, a nearly 24-hour cycle, is deeply influenced by environmental light cues. Light exposure directly affects the hypothalamus, which in turn regulates...
Sleep-Wake Cycles01:24

Sleep-Wake Cycles

Sleep is an essential physiological process vital to maintaining overall well-being. The reticular activating system (RAS), a network of neurons in the brainstem, regulates wakefulness and sleep. While it may seem passive, sleep consists of distinct cycles, each with its unique characteristics and functions. Two key sleep phases are non-rapid eye movement (NREM) and  rapid eye movement (REM).
NREM Sleep
NREM sleep comprises four progressive stages that seamlessly merge:
Overview of Metabolism01:40

Overview of Metabolism

Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
What is Metabolism?00:52

What is Metabolism?

Overview
Sedatives and Hypnotics: Overview01:23

Sedatives and Hypnotics: Overview

Sedatives are drugs that alleviate anxiety, while hypnotics induce sleep. Both classes of medication suppress neuronal activity, leading to a calming effect for sedatives and facilitating sleep for hypnotics.
Sedative-hypnotics are categorized into barbiturates, benzodiazepines (BZDs), and non-benzodiazepines or Z-drugs. These drugs work by suppressing central nervous system activity, and this suppression is dose-dependent. Older sedative medications, like barbiturates, follow a linear curve in...
Overview of Protein Metabolism01:21

Overview of Protein Metabolism

Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preclinical proof of concept for a personalized SNAP™-TIL (Specific Neo-Antigen Peptides-TIL) therapy platform.

Oncoimmunology·2026
Same author

GLP-1 receptor agonists in obstructive sleep apnea: A propensity score-matched real-world analysis.

Respiratory medicine·2026
Same author

A phase II clinical trial of albumin-bound paclitaxel, cisplatin, gemcitabine (NABPLAGEM), and paricalcitol as neoadjuvant therapy in pancreatic cancer.

The oncologist·2026
Same author

Targeting of Wnt-β-Catenin Pathway in Recurrent Ameloblastoma.

The New England journal of medicine·2026
Same author

A clinical study on the comparative effectiveness of micronutrient supplementation and physiotherapy in oral sub-mucous fibrosis.

Bioinformation·2026
Same author

Canine stress analysis of two clear aligner attachment designs: A finite element study.

Bioinformation·2026

Related Experiment Video

Updated: Jun 9, 2026

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

Sleep and metabolism: an overview.

Sunil Sharma1, Mani Kavuru

  • 1Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Brody School of Medicine, Greenville, 27834 NC, USA.

International Journal of Endocrinology
|September 3, 2010
PubMed
Summary
This summary is machine-generated.

Sleep deprivation and sleep disorders disrupt metabolic homeostasis, impacting hormonal balance and inflammation. This review explores how poor sleep alters human metabolism and its cardiovascular implications.

More Related Videos

Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings
06:39

Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings

Published on: June 13, 2025

Establishing a Device for Sleep Deprivation in Mice
05:05

Establishing a Device for Sleep Deprivation in Mice

Published on: September 22, 2023

Related Experiment Videos

Last Updated: Jun 9, 2026

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice
06:23

A Chronic Sleep Fragmentation Model using Vibrating Orbital Rotor to Induce Cognitive Deficit and Anxiety-Like Behavior in Young Wild-Type Mice

Published on: September 22, 2020

Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings
06:39

Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings

Published on: June 13, 2025

Establishing a Device for Sleep Deprivation in Mice
05:05

Establishing a Device for Sleep Deprivation in Mice

Published on: September 22, 2023

Area of Science:

  • Metabolic Science
  • Sleep Medicine
  • Endocrinology

Background:

  • Sleep is crucial for metabolic homeostasis, influencing hormonal and metabolic processes.
  • Sleep deprivation and disorders are prevalent in modern society.
  • Emerging research links sleep disturbances to significant metabolic and cardiovascular issues.

Purpose of the Study:

  • To review the intricate relationship between sleep and metabolism.
  • To elucidate how sleep deprivation and sleep disorders impact metabolic regulation.
  • To discuss the pathways involved in sleep-related metabolic dysregulation.

Main Methods:

  • Literature review of studies on sleep, metabolism, and related disorders.
  • Analysis of pathways linking sleep disturbances to metabolic changes.
  • Synthesis of current research on sleep deprivation, sleep disordered breathing, and circadian misalignment.

Main Results:

  • Sleep deprivation and disorders are associated with metabolic dysregulation.
  • Key pathways include sympathetic overstimulation, hormonal imbalance, and inflammation.
  • These disruptions have profound implications for cardiovascular health.

Conclusions:

  • Altered sleep patterns significantly impact human metabolism.
  • Understanding these mechanisms is vital for public health.
  • Further research is needed to address sleep-related metabolic disturbances.