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Related Experiment Video

Updated: Jun 9, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
07:25

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

[Prostate cancer: an update].

M Hohenfellner1

  • 1Urologische Klinik und Poliklinik, Im Neuenheimer Feld 110, 69120 Heidelberg. hohenfellner@med.uni-heidelberg.de

Der Urologe. Ausg. A
|September 3, 2010
PubMed
Summary
This summary is machine-generated.

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Active surveillance protocols can help avoid overtreatment in prostate cancer (PCa) detection. Advances in radical prostatectomy, radiation oncology, and systemic therapies are also highlighted.

Area of Science:

  • Oncology
  • Urology

Context:

  • 2009 saw significant publications on prostate cancer (PCa) management, including the S3 guideline and the European Randomized Study of Prostate Cancer Screening (ERSPC).
  • The ERSPC underscores the need for differentiated treatment beyond mere detection, emphasizing active surveillance to prevent overtreatment.

Purpose:

  • To review key advancements and ongoing discussions in prostate cancer management published in 2009.
  • To highlight evolving treatment strategies in detection, surgery, radiation oncology, and systemic therapies for prostate cancer.

Summary:

  • Active surveillance protocols are crucial for avoiding overtreatment in prostate cancer detection.
  • The therapeutic value of lymphadenectomy in radical prostatectomy (RPx) is increasingly recognized.
  • Current radiation oncology debates include brachytherapy efficacy, dose escalation in external beam radiotherapy, and adjuvant vs. salvage radiotherapy indications.

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Last Updated: Jun 9, 2026

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
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A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer

Published on: March 6, 2018

A New Technique for Treating Low-risk Prostate Cancer&#8212;Super Active Surveillance
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  • Systemic therapy advancements involve GnRH antagonists, super-antiandrogens, and prostate cancer immunotherapy approaches.

    • Impact:

    • Implementation of active surveillance can improve patient outcomes by reducing overtreatment.
    • Refined surgical and radiation techniques aim to enhance treatment efficacy and patient selection.
    • New systemic therapies offer more targeted and potentially less toxic treatment options for advanced prostate cancer.