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Updated: Jun 9, 2026

Measuring Psoriasis Severity at Home
Published on: March 1, 2024
[Psoriasis as an independent risk factor for development of coronary artery disease]
1Klinik und Poliklinik für Dermatologie und Allergologie der Technischen Universität München. davidpapo@58beats.com
Insights
Psoriasis patients have higher rates of cardiovascular disease due to shared risk factors and psoriasis potentially being an independent risk factor. Research explores common immunopathogenetic mechanisms linking these conditions.
Area of Science:
- Dermatology
- Cardiology
- Immunology
Context:
- Psoriasis is a chronic inflammatory skin disease with a frequent relapsing course.
- Psoriatic arthritis is a well-known comorbidity.
- Patients with psoriasis often exhibit classic cardiovascular risk factors like obesity, diabetes mellitus, hyperlipoproteinemia, hypertension, and nicotine abuse, frequently presenting as Metabolic Syndrome.
Purpose:
- To review the current research on the association between psoriasis and cardiovascular disease.
- To discuss potential shared immunopathogenetic mechanisms linking psoriasis and cardiovascular risk.
Summary:
- Numerous studies demonstrate that patients with psoriasis suffer more frequently from coronary heart disease compared to those without psoriasis.
- Emerging evidence suggests psoriasis may act as an independent cardiovascular risk factor, even when accounting for traditional risk factors.
- The review synthesizes current knowledge on this association and explores underlying common inflammatory pathways.
Impact:
- Highlights psoriasis as a significant factor in cardiovascular risk assessment.
- Emphasizes the need for integrated management of psoriasis and cardiovascular health.
- Provides insights into potential therapeutic targets for both conditions by understanding shared mechanisms.
Abstract:
Psoriasis is a chronic inflammatory dermatosis with a relapsing course. The best known comorbidity is psoriatic arthritis. In daily clinical practise it is well known, that patients with psoriasis show more often classic cardiovascular risk factors such as obesity, Diabetes mellitus, hyperlipoproteinemia, hypertension, nicotine abuse often presenting as Metabolic Syndrome and suffer more often from coronary heart disease than patients without psoriasis. This could be demonstrated in numerous clinical and epidemiologic studies. In the last few years there is increasing evidence for psoriasis being an independent cardiovascular risk factor despite of concomitant classic risk factors. This review summarizes the current state of research and discusses possible common immunopathogenetic mechanisms.
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