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Updated: Jun 9, 2026

Methodologies for Studying B. subtilis Biofilms as a Model for Characterizing Small Molecule Biofilm Inhibitors
Published on: October 9, 2016
[Influence of silicon dioxide and saponite on growth of Bacillus subtilis IMV B-7023]
Abstract:
Growth of Bacillus subtilis IMV B-7023 was studied under the presence of silicon dioxide and saponite cultivation in the medium. It was established that the adding ofthese materials into the medium affects significantly the bacteria growth activity. Efficiency and orientation of the process depends on the type of dispersed material and contents of phosphate in the cultivation medium. Thus, under the concentration of 0.6 g/l PO4(3-) saponite stimulates the growth of bacteria but at a lower concentration (0.1 g/l PO4(3-)) growth activity of microorganisms becomes lower. At the same time in the presence of silicon dioxide the stimulation of bacterial growth is observed at different concentrations of phosphate in the medium. It is shown that the present effect is not the result of the phosphate sorption on the surface of the investigated dispersed materials. The contact interaction of solid particles with bacterial cells was found.

