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Updated: Jun 9, 2026

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

Published on: July 22, 2021

Synovial hypertrophy causing recurrent hemarthrosis after total knee replacement.

Shreyash M Gajjar¹, Andrew Platts, George Dowd

¹Department of Knee Surgery, Royal Free NHS and Wellington Hospitals, London, United Kingdom. drsgajjar@yahoo.com

The Journal of Knee Surgery

|September 4, 2010

Summary

Recurrent hemarthrosis after total knee replacement is rare. Synovial hypertrophy and impingement causing this issue were successfully treated with embolization in three patients.

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Last Updated: Jun 9, 2026

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint

Published on: July 22, 2021

Area of Science:

Orthopedic surgery
Vascular interventional radiology

Background:

Recurrent hemarthrosis post-total knee replacement (TKR) presents diagnostic challenges.
Identifying the underlying cause is crucial for effective management.

Observation:

Three patients experienced late-onset recurrent hemarthrosis after TKR.
The cause was identified as synovial hypertrophy and impingement.

Findings:

Successful treatment of recurrent hemarthrosis was achieved through embolization.
Embolization effectively addressed the vascular component of synovial hypertrophy.

Implications:

Embolization is a viable treatment option for late-onset hemarthrosis due to synovial hypertrophy post-TKR.
This approach may prevent further joint damage and improve patient outcomes.