Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Structural Joints: Fibrous Joints

Structural Joints: Fibrous Joints

Fibrous joints are a type of joint where the bones are connected by fibrous connective tissue. These joints provide stability and minimal to no movement between the articulating bones. There are three types of fibrous joints.
Suture
All the bones of the skull, except for the mandible, are joined to each other by a fibrous joint called a suture. The fibrous connective tissue found at a suture strongly unites the adjacent skull bones and thus helps to protect the brain and form the face. In...

Cellular Adaptation IV: Dysplasia and Metaplasia

Cellular Adaptation IV: Dysplasia and Metaplasia

DysplasiaDysplasia refers to abnormal changes in the size, shape, and organization of mature cells, characterized by pleomorphism, nuclear abnormalities, and increased mitotic activity. It commonly affects epithelial tissues, including the cervix, gastrointestinal tract, respiratory mucosa, and endometrium. Although it may occur alongside hyperplasia, dysplasia is not a true adaptive response but a preneoplastic change with potential to progress to cancer.When confined above the basement...

Sutures of the Skull

Sutures of the Skull

The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...

Fibrous Proteins

Fibrous Proteins

Fibrous proteins are either long and narrow proteins or assemble to form long and thin structures. They contain repetitive units and usually consist of either alpha helices or beta sheets and, in rare cases, a mix of both. The amino acids in the primary structure often consist of repeating amino acid sequences. The role of fibrous proteins is primarily structural. Many are located in the extracellular matrix and are present in connective tissues to impart strength and joint mobility. They are...

Structural Joints: Cartilaginous Joints

Structural Joints: Cartilaginous Joints

As the name indicates, at a cartilaginous joint, the adjacent bones are united by cartilage, a tough but flexible type of connective tissue. Unlike synovial joints, these types of joints lack a joint cavity and involve bones joined together by either hyaline cartilage or fibrocartilage.
There are two types of cartilaginous joints:
Synchondrosis
A synchondrosis ("joined by cartilage") is a cartilaginous joint where bones are connected by hyaline cartilage. Synchondrosis may be temporary or...

Growth of Cartilage and Bone Tissue

Growth of Cartilage and Bone Tissue

Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Early genetic evolution of driver mutations in uveal melanoma.

Nature communications·2025

Same author

Early Genetic Evolution of Driver Mutations in Uveal Melanoma.

medRxiv : the preprint server for health sciences·2025

Same author

Long-Term Clinical Outcomes for Adolescent and Young-Adult Uveal Melanoma Patients Treated with Dedicated Particle-Beam Radiation.

Cancers·2025

Same author

Novel Risk Factors for Uveal Melanoma in Adolescent and Young Adult Patients: A Comprehensive Case-Control Analysis.

Ophthalmology science·2025

Same author

Alzheimer Disease Anti-Amyloid Immunotherapies: Imaging Recommendations and Practice Considerations for Monitoring of Amyloid-Related Imaging Abnormalities.

AJNR. American journal of neuroradiology·2024

Same author

15-Gene Expression Profile and <i>PRAME</i> as Integrated Prognostic Test for Uveal Melanoma: First Report of Collaborative Ocular Oncology Group Study No. 2 (COOG2.1).

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2024

Same journal

Prospective validation of transcutaneous levator recession for non-thyroid lid retraction: efficacy, safety, and predictable outcomes.

Orbit (Amsterdam, Netherlands)·2026

Same journal

Impact of COVID-19 on demographic trends and predictors of surgical interventions in pediatric orbital cellulitis.

Orbit (Amsterdam, Netherlands)·2026

Same journal

Drug-associated lacrimal drainage obstruction: a population-based pharmacovigilance study.

Orbit (Amsterdam, Netherlands)·2026

Same journal

Re: "A new surgical technique for excision of orbital cavernous hemangioma: a 15-year experience".

Orbit (Amsterdam, Netherlands)·2026

Same journal

Study of the toxic effect of benzalkonium chloride on epithelial cells of the lacrimal canaliculi.

Orbit (Amsterdam, Netherlands)·2026

Same journal

Orbital venous-flow malformations: is terminology complicating management in the <i>AI</i> era?

Orbit (Amsterdam, Netherlands)·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 9, 2026

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects

Published on: April 11, 2012

Fibrous dysplasia.

Devron H Char¹, Jerome A Barakos, Charles S Cobbs

¹The Tumori Foundation, 45 Castro Street, Suite 309, San Francisco, CA 94114, USA. devron@tumori.org

Orbit (Amsterdam, Netherlands)

|September 4, 2010

Summary

This summary is machine-generated.

This case report details an unusual fibrous dysplasia presentation featuring a large cystic component. Magnetic Resonance (MR) imaging findings were inconclusive for diagnosis.

More Related Videos

A Rat Tibial Growth Plate Injury Model to Characterize Repair Mechanisms and Evaluate Growth Plate Regeneration Strategies

A Rat Tibial Growth Plate Injury Model to Characterize Repair Mechanisms and Evaluate Growth Plate Regeneration Strategies

Published on: July 4, 2017

Surgical Technique of the 3-Dimensional-printed Personalized Hip Implant for the Treatment of Canine Hip Dysplasia

Surgical Technique of the 3-Dimensional-printed Personalized Hip Implant for the Treatment of Canine Hip Dysplasia

Published on: April 19, 2024

Related Experiment Videos

Last Updated: Jun 9, 2026

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects

Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects

Published on: April 11, 2012

A Rat Tibial Growth Plate Injury Model to Characterize Repair Mechanisms and Evaluate Growth Plate Regeneration Strategies

A Rat Tibial Growth Plate Injury Model to Characterize Repair Mechanisms and Evaluate Growth Plate Regeneration Strategies

Published on: July 4, 2017

Surgical Technique of the 3-Dimensional-printed Personalized Hip Implant for the Treatment of Canine Hip Dysplasia

Surgical Technique of the 3-Dimensional-printed Personalized Hip Implant for the Treatment of Canine Hip Dysplasia

Published on: April 19, 2024

Area of Science:

Radiology
Pathology
Oncology

Background:

Fibrous dysplasia is a benign bone disorder where normal bone is replaced by fibrous tissue.
It can affect single or multiple bones and present with diverse clinical and radiological features.

Observation:

A rare case of fibrous dysplasia with an exceptionally large cystic component is presented.
This atypical morphology posed diagnostic challenges on Magnetic Resonance (MR) imaging.

Findings:

The MR imaging pattern of this fibrous dysplasia case was not diagnostic.
The significant cystic component deviated from typical presentations, complicating initial assessment.

Implications:

Highlights the importance of considering rare presentations of common conditions.
Emphasizes the need for integrated diagnostic approaches when imaging findings are ambiguous.
Suggests further investigation into the imaging characteristics of cystic fibrous dysplasia.