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Updated: Jun 9, 2026

Chronic Ovine Model of Right Ventricular Failure and Functional Tricuspid Regurgitation
Published on: March 17, 2023
Basis for intervention on functional tricuspid regurgitation.
Shahzad G Raja1, Gilles D Dreyfus
1Department of Cardiothoracic Surgery, Great Ormond Street Hospital, London, United Kingdom. drrajashahzad@hotmail.com
Functional tricuspid regurgitation is a serious heart valve condition, not a benign issue. Current repair methods often fail, leading to residual or recurrent regurgitation, impacting survival.
Area of Science:
- Cardiology
- Cardiac Surgery
- Valvular Heart Disease
Background:
- Functional tricuspid regurgitation (FTR) is a complex valvular lesion with controversial management.
- It is no longer considered benign and does not resolve spontaneously after left-sided valve correction.
- FTR significantly increases morbidity and adversely affects patient survival.
Purpose of the Study:
- To review emerging concepts and advances in understanding functional tricuspid regurgitation.
- To define the basis for intervention in cases of functional tricuspid regurgitation.
- To address uncertainties in diagnosis, surgical indication, procedure choice, and late surgical outcomes.
Main Methods:
- This is a review article.
- It synthesizes current understanding and emerging concepts in FTR.
- It analyzes the limitations of existing surgical techniques.
Main Results:
- Current repair techniques for FTR often result in significant residual or recurrent regurgitation.
- Failure to address all components of FTR contributes to suboptimal outcomes.
- Optimal management strategies and late results remain areas of active investigation.
Conclusions:
- Functional tricuspid regurgitation is a significant clinical problem requiring careful consideration.
- Advances in understanding are crucial for improving diagnostic accuracy and treatment efficacy.
- Further research is needed to refine surgical indications and techniques for better long-term results.
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