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Consumers' views of pharmacogenetics--A qualitative study
Catherine A Haddy1, Helena M Ward, Manya T Angley
1School of Pharmacy and Medical Sciences, Sansom Institute, University of South Australia, Frome Road, Adelaide 5000, South Australia.
Consumers desire personalized medicine (PGx) but have concerns about side effects, cost, and data privacy. Education for healthcare providers is crucial for successful implementation of pharmacogenetics (PGx).
Area of Science:
- Pharmacogenetics and personalized medicine.
- Public health and adverse drug reactions.
- Consumer perceptions and healthcare implementation.
Background:
- Adverse drug reactions pose a significant public health challenge.
- Pharmacogenetics (PGx) offers potential for personalized medication dosing but is underutilized.
- Limited research exists on consumer perspectives regarding PGx implementation barriers.
Purpose of the Study:
- To explore public views on medication use and side effects.
- To understand consumer opinions on pharmacogenetics (PGx) and its implementation.
- To identify perceived barriers to integrating PGx into clinical practice.
Main Methods:
- Qualitative analysis of 5 focus groups (n=35) with individuals affected by chronic conditions.
- Discussions covered medication experiences and views on PGx, termed "Personalized Medicine".
- Framework approach used for data analysis, with independent coding and thematic comparison.
Main Results:
- Participants expressed a desire for holistic disease management and medication selection.
- Concerns were raised about medication side effects, genetic information privacy, and implementation costs.
- Focus group participants identified potential barriers to pharmacogenetics (PGx) adoption.
Conclusions:
- Pharmacogenetics (PGx) testing is viewed positively if integrated with broader patient factors.
- Effective communication and comprehensive information from healthcare professionals are essential.
- Education for clinicians and pharmacists is vital to meet consumer expectations for PGx implementation.
Related Concept Videos
Pharmacogenetics and Pharmacogenomics: Overview
Principles of Pharmacogenetics: Types of Genetic Variants
Pharmacogenetic Phenotypes: Alterations in Pharmacokinetics, Drug Targets and Biologic Milieu
Pharmacogenetics of Drug Metabolism: Overview
Pharmacogenomics: Identification of New Drug Targets
Pharmacogenetics of Drug Transporters: P-Glycoprotein and Solute Carrier Transporters
