Related Experiment Video
Updated: Jun 9, 2026

Analyses of Proteinuria, Renal Infiltration of Leukocytes, and Renal Deposition of Proteins in Lupus-prone MRL/lpr Mice
Published on: June 8, 2022
[Pathological classification and clinical characteristics of lupus nephritis: a report of 49 cases]
Yun Liu1, Hai-feng Yang, Li-xin Wang
1Center of Nephrology, Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510120, China. iooi0302@163.com
Objective:
To evaluate the relation between the pathological features of lupus nephritis (LN) and the clinical activity and laboratory examination.
Methods:
Renal biopsies were obtained from 49 cases of lupus nephritis and classified according to ISN/RPS(2003) classification. The clinical activity, laboratory results and the renal pathological features of the disease were analyzed.
Results:
All the cases showed pathologies in the kidney. Type IV and V LN cases had a high incidence of nephrotic syndrome, and type II and III cases frequently showed latent nephritis. The NIH index and biopsy index indicated the degree of pathological lesions and were significantly related to the clinical features. Nearly all the indexes including NIH index, biopsy index, the clinical activity and the laboratory examination suggested stronger activity of type IV LN than the other types.
Conclusion:
The pathological changes, clinical activity and laboratory examination results of LN are related with each other. The clinical activity and laboratory examination of LN can be used to estimate the pathological type and degree of renal lesion in LN.
More Related Videos
Related Concept Videos
Nephrotic Syndrome I : Introduction
Nephrotic Syndrome II : Assessment and Medical Management
Nephrons
Nephrotic Syndrome III : Nursing Management
Acute Pyelonephritis II: Diagnostic Studies and Management
Acute Pyelonephritis I: Introduction
