Related Experiment Video
Updated: Jun 9, 2026

07:44
Transforaminal Full-Endoscopic Lumbar Foraminotomy Under Local Anesthesia for L5/S1 Adjacent Segment Foraminal Stenosis
Published on: October 17, 2025
[Lumbar epidural and foraminal injections: update].
1Service de Radiologie Ostéo-articulaire, Hôpital Lariboisière, AP-HP, 2 rue Ambroise Paré, 75010 Paris, France. marc.wybier@lrb.aphp.fr
Journal De Radiologie
|September 4, 2010
Summary
Fluoroscopy-guided lumbar spine injections can cause paralysis due to arterial ischemia. Prior surgery and specific steroid use, like prednisolone acetate, may increase risks of this serious complication.
Area of Science:
- Neurology
- Radiology
- Interventional Pain Management
Background:
- Fluoroscopy-guided lumbar spine injections are common procedures.
- Potential complications include neurological deficits such as paralysis.
- Understanding risk factors is crucial for patient safety.
Observation:
- A review of 12 cases (2002-2008) of immediate paralysis following fluoroscopy-guided lumbar spine injections.
- Magnetic Resonance (MR) imaging revealed spinal cord ischemia of arterial origin in affected patients.
- Common factors included prior lumbar surgery and specific injection approaches.
Findings:
- Prior lumbar spine surgery appears to increase the risk of paraplegia, potentially due to scar tissue.
- Different injection routes (transforaminal, interlaminar, juxta-zygapophyseal) were used, particularly in patients with previous surgery.
- The frequent use of prednisolone acetate in France may contribute to cases due to its propensity for macro-aggregate formation and subsequent embolization.
Implications:
- These findings highlight the potential risk of spinal cord ischemia and paralysis after lumbar spine injections.
- Identifying patients with prior surgery and considering alternative steroid formulations may mitigate risks.
- Further research into the mechanism of arterial embolization is warranted to improve procedural safety.
Related Concept Videos
Local Anesthetics: Clinical Application as Epidural Anesthesia
Epidural anesthetics are administered in the fat-filled epidural space, the outermost part of the spinal canal. This technique is commonly employed for pain management and anesthesia during lower abdomen and pelvis surgeries or labor and delivery.
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Local Anesthetics: Clinical Application as Spinal Anesthesia
Spinal anesthetics are given during lower abdomen and limb surgeries to block sensory and motor neurons. They are administered in the mid to low lumbar regions, primarily acting on the cauda equina's nerve roots. The blockade level depends on the local anesthetic (LA) concentration. Usually, low LA concentrations are sufficient to block sensory fibers, while only high LA concentrations block motor fibers. Other factors like injection volume and speed, the patient's posture, and the drug...
Herniated Intervertebral Disc l: Introduction
Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...
