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Cognitive dysfunction and associated factors in patients with chronic schizophrenia
Latha Srinivasan1, R Thara, S N Tirupati
1Psychologist, Hunter New England Area Health Service, Australia.
Indian Journal of Psychiatry
|September 4, 2010
Summary
Indian patients with schizophrenia exhibit significant neurocognitive deficits in attention, executive function, and memory compared to controls. These deficits are linked to illness duration and symptom severity.
Area of Science:
- Neuroscience
- Psychiatry
Background:
- Neurocognitive deficits are characteristic of schizophrenia, influencing clinical presentation and disease progression.
- Investigating cognitive dysfunction in Indian schizophrenia patients is crucial due to the illness's potentially milder course in this region.
Purpose of the Study:
- To assess cognitive deficits in chronic schizophrenia patients in India.
- To identify factors associated with cognitive impairment in this population.
- To compare cognitive function between patients and healthy controls.
Main Methods:
- A comparative study involving 100 patients with chronic schizophrenia and 100 matched healthy controls.
- Assessment of attention, executive function, and memory using standardized tests.
Main Results:
- Patients with schizophrenia demonstrated poorer performance across all cognitive domains compared to the control group.
- Cognitive deficits were correlated with demographic factors (gender, education, age) and clinical variables (illness duration, positive/negative symptoms).
Conclusions:
- The neurocognitive profile of Indian patients with chronic schizophrenia aligns with findings from studies in developed countries.
- These results underscore the global nature of schizophrenia-related cognitive impairments.
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