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Idiopathic CD4 lymphocytopenia presenting as refractory cryptococcal meningitis
1Department of Neurology, Postgraduate Institute of Medical Education and Research, Chandigarh-160 012, India.
Abstract:
Idiopathic CD4 T-lymphocytopenia (ICL) is a syndrome characterized by depletion of CD4 T-cells without evidence of human immunodeficiency virus (HIV) infection. There are a few reported cases of ICL associated with different diseases and clinical conditions, most commonly the opportunistic infections like Tuberculosis, fungal and parasitic diseases which are also seen in HIV-positive patients. We report a case without risk factors or laboratory evidence of HIV infection who presented with refractory cryptococcal meningitis and was found to have ICL.
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