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Published on: July 24, 2016
Tick-borne meningoencephalitis in a 4.5-month-old infant
1Pediatrics, Medical Center Coburg, Ketschendorferstraße 33, Coburg, Germany.
Insights
Tick-borne encephalitis (TBE) can cause severe meningoencephalitis in infants, contrary to the belief of mild TBE cases. Early diagnosis and prophylactic measures are crucial for infant TBE prevention.
Area of Science:
- Pediatric Neurology
- Infectious Diseases
- Virology
Background:
- Tick-borne encephalitis (TBE) is generally considered mild in children, but severe neurological sequelae are documented.
- Infantile TBE cases are rare, with limited data on their clinical course and outcomes.
Observation:
- A 4.5-month-old infant in Germany developed acute meningoencephalitis following a tick bite.
- Symptoms included fever, seizures, and confirmed TBE virus infection via CSF analysis.
Findings:
- This case represents the first documented infant TBE in Germany.
- Neurological follow-up revealed no abnormalities in this infant.
- Analysis of three additional published infant TBE cases indicates significant morbidity.
Implications:
- Infant TBE can present as acute meningoencephalitis with considerable neurological burden.
- Parental transmission of ticks highlights the need for infant exposure-prophylactic measures.
- Raising awareness among parents and healthcare providers about TBE risks in infants is essential.
Background:
The course of tick-borne encephalitis (TBE) in children is supposed to be mild though severe neurological sequelae have been reported. Only occasionally infants are affected.
Patients And Methods:
Case report, review of literature.
Results:
We describe the first case of tick-borne encephalitis in a 4.5-month-old male infant in Germany. 11 days after a tick-bite he developed acute illness with fever, focal and generalized seizures. Meningoencephalitis caused by the TBE virus was diagnosed by cerebrospinal fluid (CSF) pleocytosis and detection of TBE-RNA in the CSF. Neurological follow-up showed no abnormalities.
Conclusions:
The acute meningoencephalitis in the present case and the neurological short and long term morbidity of 3 additional published cases of TBE suggest the considerable burden of this disease in infancy. As parents can transmit the tick to their infant informations about exposure-prophylactic measurements are recommended.
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