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A fluorescent rosamine compound selectively stains pluripotent stem cells

Chang-Nim Im1, Nam-Young Kang, Hyung-Ho Ha

  • 1Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Republic of Singapore.

Angewandte Chemie (International Ed. in English)
|September 4, 2010
PubMed
Summary

No abstract available in PubMed .

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Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore called induced pluripotent stem...