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Urinary calculi associated with purine metabolism. Uric acid nephrolithiasis
1Division of Nephrology and Internal Medicine, Mayo Clinic, Rochester, Minnesota.
Endocrinology and Metabolism Clinics of North America
|December 1, 1990
Abstract:
Uric acid stones are the consequences of abnormalities in purine metabolism, urate/uric acid renal handling, or excess dietary protein. Treatment is aimed at preventing additional formation by decreasing the degree of urate and uric acid supersaturation in urine, by altering diet, fluid intake, and the urine pH, and by blocking steps in uric acid production.