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[Chemical constituents of roots of Saposhnikovia divaricata]
Bo Zhao1, Xinbao Yang, Xiuwei Yang
1College of Traditional Chinese Medicine, Jilin Agricultural University, Changchun 130118, China.
Objective:
To study the chemical constituents in the dried roots of Saposhnikovia divaricata.
Method:
The chemical constituents were isolated by various column chromatographic methods and structurally elucidated by IR, UV, MS and NMR evidences.
Result:
Eighteen compounds were obtained and identified as 3'-O-angeloylhamaudol (1), isobergapten (2), imperatorin (3), pentacosane acid (4), anomalin (5), decursin (6), 5-methoxy-7-(3,3-dimethylallyl- oxy)coumarin (7), decursinol angelate (8), xanthotoxin (9), bergapten (10), tectochrysin (11), scopoletin (12), hamaudol (13), ledebouriellol (14), cimifugin (15), sec-O-glucosylhamaudol (16), 4'-O-beta-D-glucosyl-5-O-methylvisamminol (17), and prim-O-glucosylcimifugin (18).
Conclusion:
Compounds 2, 6-8, and 11 were isolated from the roots of S. divaricata for the first time. Compounds 1 and 13-18 were chromones, 2, 3, 5-10 and 12 were coumarins, 4 was fatty acid, and 11 was flavonoid.
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