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Construction of Cyclic Cell-Penetrating Peptides for Enhanced Penetration of Biological Barriers
Published on: September 19, 2022
Noncationic dipeptide mimic oligomers as cell penetrating nonpeptides (CPNP)
Lubomir L Vezenkov1, Marie Maynadier, Jean-François Hernandez
1Institut des Biomolécules Max Mousseron, UMR5247 CNRS, Universités Montpellier 1 et 2, Montpellier, France.
Bioconjugate Chemistry
|September 7, 2010
Abstract:
Small oligomers of constrained dipeptide mimics have been synthesized as new vectors for intracellular delivery. They are highly internalized by cells and delivered to the lysosomes by an energy-dependent pathway. This new class of vectors referred to as cell penetrating nonpeptides (CPNP) possess the distinctive feature of being noncationic.

