Early identification and delay to treatment in myocardial infarction and stroke: differences and similarities

Johan Herlitz1, Birgitta Wireklintsundström, Angela Bång

  • 1Institute of Medicine, Department of Molecular and Clinical Medicine, Sahlgrenska University Hospital, SE-413 45 Göteborg, Sweden. johan.herlitz@gu.se

Insights

Minutes matter for acute myocardial infarction (AMI) and acute ischemic stroke. While AMI patients often suspect their condition more, stroke patients utilize emergency services more, yet AMI treatment is faster. Both require improved early detection and faster treatment initiation.

Area of Science:

  • Cardiology
  • Neurology
  • Emergency Medicine

Background:

  • Acute myocardial infarction (AMI) and acute ischemic stroke are life-threatening atherosclerosis complications.
  • Early intervention is crucial for limiting organ damage in both conditions.
  • Pre-hospital care and patient/provider actions are critical in the acute phase.

Purpose of the Study:

  • To compare pre-hospital patient, bystander, and healthcare provider actions in acute myocardial infarction (AMI) and acute ischemic stroke.
  • To identify similarities and differences in the acute management of AMI and stroke.

Main Methods:

  • A literature search was conducted using PubMed, Embase, and Cochrane Library databases.

Main Results:

  • Patients more frequently suspect AMI than stroke, with a gender gap in AMI suspicion.
  • Emergency Medical Service (EMS) use is higher for stroke, but hospital admission delay is shorter for AMI.
  • Diagnostic tools for EMS are more advanced for AMI; knowledge of early treatment importance impacts delays in both.

Conclusions:

  • Despite the 'fast track' concept, treatment initiation is still faster for AMI than stroke.
  • Improving early detection and reducing treatment delays are future priorities for both conditions.
  • Collaboration between cardiologists, neurologists, and pre- and in-hospital care teams is recommended.
Abstract

Related Concept Videos

Acute Coronary Syndrome I: Introduction01:30

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Ischemic Stroke l: Introduction01:15

Ischemic Stroke l: Introduction

Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.
Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and narrowing...
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...