Related Experiment Video
Updated: Jun 9, 2026
14:43
A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
Published on: January 12, 2018
The role of prevention
1Cleveland Clinic Lerner College of Medicine, Department of Neurology, Headache Center, Cleveland Clinic, Cleveland, OH 44195, USA. teppers@ccf.org
Handbook of Clinical Neurology
|September 7, 2010
Summary
Daily migraine prevention medication is recommended for frequent, disabling migraines. Effective treatment involves careful drug selection based on comorbidities, gradual dose titration, and a minimum 2-3 month trial with headache diary monitoring.
Area of Science:
- Neurology
- Pharmacology
Background:
- Daily preventive medication is crucial for managing high-frequency and high-disability migraines.
- Selecting the right medication requires considering patient comorbidities for simultaneous treatment.
- Evidence-based guidelines should inform preventive drug selection.
Purpose of the Study:
- To outline the principles of initiating and managing daily preventive migraine medication.
- To identify factors associated with successful and unsuccessful treatment outcomes.
- To highlight medications with the strongest evidence for migraine prevention.
Main Methods:
- Initiate treatment with a low dose of the selected preventive medication.
- Gradually increase the dose to achieve an effective level.
- Monitor treatment outcomes using a headache diary for at least 2-3 months.
Main Results:
- Poor outcomes in migraine prevention are linked to incorrect drug choice, improper dosing, insufficient treatment duration, or unrealistic patient expectations.
- The highest level of evidence supports the use of amitriptyline, propranolol, timolol, valproate, and topiramate for migraine prevention.
Conclusions:
- Effective migraine prevention requires a systematic approach to medication selection and management.
- Adherence to evidence-based practices and patient monitoring improves treatment success.
- Specific medications demonstrate superior efficacy for daily migraine prophylaxis.
Related Concept Videos
01:30Preventive Healthcare Services
Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:
01:26Levels of Health Promotion and Illness Prevention
Health promotion allows a person to control the determinants of health, resulting in an improved health status. It enhances the quality of life and reduces premature deaths. Health promotion and illness prevention programs help people make beneficial choices to reduce the risk of disease and disabilities. There are three health promotion and illness prevention levels: primary, secondary, and tertiary prevention.
In primary prevention, actions taken before disease onset prevent the disease from...
In primary prevention, actions taken before disease onset prevent the disease from...
01:22Healthcare Associated Infections II: Preventive Measures
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
02:59Cancer Prevention
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
02:59Cancer Prevention
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
01:18Models of Health Promotion and Illness Prevention II
The person's health status fluctuates continually, varying from being in good health to becoming ill and returning to being healthy. To understand the concept of illness prevention, there are two models. First, the health-illness continuum model is a graphic representation of an individual's wellness. It states that a person is considered healthy in the absence of physical disease and the presence of good emotional health.
The agent-host-environment model states that disease results from...
The agent-host-environment model states that disease results from...