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Updated: Jun 9, 2026

Surgical Treatment of an Endolymphatic Sac Tumor
Published on: May 26, 2023
Sacrococcygeal yolk sac tumor presenting as subcutaneous fluid collection initially treated as abscess
Azher Merchant1, Rosalyn W Stewart
1Pediatric Emergency Department, University of Maryland, Baltimore, MD, USA.
Insights
Rare malignant extragonadal germ cell tumors can present as skin nodules in children. This case highlights a sacrococcygeal yolk sac tumor initially mistaken for a soft tissue abscess.
Area of Science:
- Oncology
- Pediatric Oncology
- Pathology
Background:
- Malignant extragonadal germ cell tumors (EGGCTs) are rare, particularly in pediatric populations.
- These tumors arise along the body's midline, potentially presenting with both internal and external symptoms.
- Early diagnosis is crucial, yet EGGCTs can mimic more common benign conditions.
Observation:
- A case report details an 11-month-old female infant with a sacrococcygeal EGGCT.
- The tumor initially manifested as a draining subcutaneous nodule.
- The presentation was initially misdiagnosed and treated as a soft tissue abscess.
Findings:
- The study identified a sacrococcygeal extragonadal yolk sac tumor in an infant.
- The tumor's external manifestation mimicked a benign soft tissue condition, leading to delayed diagnosis.
- This highlights the diagnostic challenges associated with extragonadal germ cell tumors.
Implications:
- Accurate diagnosis of EGGCTs requires high clinical suspicion, especially with midline masses in children.
- Awareness of EGGCTs' potential to mimic benign conditions is vital for pediatricians and oncologists.
- This case underscores the importance of considering rare diagnoses in pediatric soft tissue presentations.
Abstract:
Malignant extragonadal germ cell tumors, though more common in infants and children, are rare. They occur in the body's midline and may have internal and external manifestations. We report a case of an 11-month-old female with sacrococcygeal extragonadal yolk sac tumor manifesting as a draining subcutaneous nodule after initial treatment as an abscess. Extragonadal germ cell tumors can present with external manifestations confusingly similar to other more benign soft tissue conditions.
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