Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

The Pineal Gland

The Pineal Gland

The pineal gland, a diminutive endocrine structure named for its pinecone-shaped appearance, is situated atop the third ventricle within the diencephalon region of the forebrain. This gland, composed of secretory cells known as pinealocytes arranged in compact cords and clusters around dense particles of calcium salts, plays a pivotal role in hormonal regulation.
The primary secretion of the pineal gland is the hormone melatonin, derived from serotonin. The concentration of melatonin in the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Hemorrhagic Cardiac Tamponade Associated with Apixaban: A Case Report and Systematic Review of Literature.

Cardiovascular revascularization medicine : including molecular interventions·2019

Same author

Aneurysmal dilatation of pericardial patch closure of ventricular septal defect.

European heart journal. Case reports·2019

Same author

Pulmonary arterial hypertension: a clot in question.

The Journal of the Oklahoma State Medical Association·2014

Same author

Patient prompting of their physician resulted in increased colon cancer screening referrals.

World journal of gastrointestinal oncology·2014

Same author

Non-autoimmune hemolytic anemia with clostridium ramosum bacteremia.

Clinical medicine. Case reports·2013

Same author

Obesity, brain natriuretic peptide levels and mortality in patients hospitalized with heart failure and preserved left ventricular systolic function.

The American journal of the medical sciences·2013

Search research articles

Related Experiment Video

Updated: Jun 9, 2026

Endoscopic Third Ventriculostomy and Pineal Biopsy from a Single Entry Point

Endoscopic Third Ventriculostomy and Pineal Biopsy from a Single Entry Point

Published on: June 28, 2024

Pineal germinoma.

Nandakumar Srinivasan¹, Aneesh Pakala, Chandana Mukkamalla

¹Department of Internal Medicine, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. drnandos@yahoo.com

Southern Medical Journal

|September 7, 2010

Summary

This study reports a rare case of pineal germinoma in an adult, diagnosed via cerebrospinal fluid cytology. This highlights an alternative diagnostic method for this uncommon central nervous system germinoma.

More Related Videos

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma

Published on: February 22, 2015

Using the Chick Embryo Brain as a Model for In Vivo and Ex Vivo Analyses of Human Glioblastoma Cell Behavior

Using the Chick Embryo Brain as a Model for In Vivo and Ex Vivo Analyses of Human Glioblastoma Cell Behavior

Published on: May 26, 2023

Related Experiment Videos

Last Updated: Jun 9, 2026

Endoscopic Third Ventriculostomy and Pineal Biopsy from a Single Entry Point

Endoscopic Third Ventriculostomy and Pineal Biopsy from a Single Entry Point

Published on: June 28, 2024

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma

Transposon Mediated Integration of Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel Models of Glioblastoma

Published on: February 22, 2015

Using the Chick Embryo Brain as a Model for In Vivo and Ex Vivo Analyses of Human Glioblastoma Cell Behavior

Using the Chick Embryo Brain as a Model for In Vivo and Ex Vivo Analyses of Human Glioblastoma Cell Behavior

Published on: May 26, 2023

Area of Science:

Neuro-oncology
Pathology

Background:

Germinomas are gonadal neoplasms, infrequently found extragonadally in midline structures.
Pineal gland germinomas are exceptionally rare in adults, with most cases diagnosed in adolescence.

Observation:

This report details a unique case of a pineal germinoma diagnosed in an adult patient.
Diagnosis was achieved through cerebrospinal fluid cytology, an atypical method for this tumor.

Findings:

Cerebrospinal fluid cytology can be a viable diagnostic tool for adult pineal germinomas.
Literature review from 1983-2009 on pineal germinomas was conducted using PubMed and OVID.

Implications:

This case expands the diagnostic possibilities for adult pineal germinomas.
Highlights the importance of considering less common diagnostic pathways in rare oncological presentations.