Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions.

Annals of clinical and translational neurology·2026
Same author

Molecular, cellular and network mapping of brain structural deviations in patients with Post-COVID19 syndrome.

Brain, behavior, & immunity - health·2026
Same author

The association between autistic traits and trajectories of anxiety in middle-aged and older adults: an 8-year growth mixture model analysis.

Nature. Mental health·2026
Same author

Brain dynamics of attentional, default-mode and limbic networks are disrupted at rest in post-COVID-19 syndrome.

Brain, behavior, & immunity - health·2026
Same author

Cross-sectional and longitudinal associations of self-perceptions of aging with physical activity in multimorbidity: The role of depressive symptoms.

Archives of gerontology and geriatrics·2026
Same author

Autistic traits and suicidality in midlife and old age: investigating mediating effects of mental health and social connectedness.

Nature. Mental health·2026

Related Experiment Video

Updated: Jun 9, 2026

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
12:21

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

Reduced brain white matter integrity in trichotillomania: a diffusion tensor imaging study.

Samuel R Chamberlain1, Adam Hampshire, Lara A Menzies

  • 1Department of Psychiatry and Medical Research Council, Wellcome Trust Behavioural and Clinical Neurosciences Institute, University of Cambridge, England. srchamb@gmail.com

Archives of General Psychiatry
|September 8, 2010
PubMed
Summary

Individuals with trichotillomania (pathological hair pulling) show altered white matter integrity in brain regions crucial for motor control and emotional regulation. These changes in fractional anisotropy were not linked to symptom severity or depression.

More Related Videos

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
10:43

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

Published on: July 1, 2014

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

Related Experiment Videos

Last Updated: Jun 9, 2026

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging
12:21

Probing the Brain in Autism Using fMRI and Diffusion Tensor Imaging

Published on: September 12, 2011

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity
10:43

Developing Neuroimaging Phenotypes of the Default Mode Network in PTSD: Integrating the Resting State, Working Memory, and Structural Connectivity

Published on: July 1, 2014

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

Area of Science:

  • Neuroscience
  • Psychiatry
  • Neuroimaging

Background:

  • Trichotillomania is a disorder defined by compulsive hair pulling.
  • Understanding its neurobiological underpinnings is crucial for effective treatment.

Purpose of the Study:

  • To investigate white matter tract integrity in individuals diagnosed with trichotillomania.
  • To explore the relationship between white matter abnormalities, symptom severity, and mood.

Main Methods:

  • Diffusion tensor imaging (DTI) was used to measure fractional anisotropy (FA) in 18 participants with trichotillomania and 19 healthy controls.
  • Statistical analyses included between-group comparisons with permutation cluster analysis and correction for multiple comparisons.
  • The Massachusetts General Hospital Hairpulling Scale and Montgomery-Asberg Depression Rating Scale assessed symptom severity and dysphoria.

Main Results:

  • Participants with trichotillomania demonstrated significantly reduced FA in the anterior cingulate cortex, presupplementary motor area, and temporal cortex.
  • No significant correlation was found between FA values and the severity of trichotillomania or depressive symptoms.

Conclusions:

  • The findings suggest that disruptions in white matter pathways involved in motor control, habit formation, and emotional processing contribute to the pathophysiology of trichotillomania.
  • These white matter alterations may play a role in the compulsive nature of hair pulling and associated mood disturbances.