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[Studies on pharmacologically active principles from Indonesian crude drugs. III. Toxic components from Brucea
E Okuyama1, L H Gao, M Yamazaki
1Faculty of Pharmaceutical Sciences, Chiba University, Japan.
Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan
|November 1, 1990
Abstract:
During our screening of pharmacologically active principles from Indonesian medicinal plants by a hypothermic effect the methanol-extract of Brucea javanica (L.) Merr. has been found to exhibit a lethal toxicity to mice. The toxic components were isolated and identified with bruceoside A and B and yadanzioside F. Correction of 13C-nuclear magnetic resonance assignment was also mentioned.