Related Experiment Video
Updated: Jun 9, 2026

Confocal Microscopy Reveals Cell Surface Receptor Aggregation Through Image Correlation Spectroscopy
Published on: August 2, 2018
Intensity correlation of a two-frequency wave at the finite-aperture detector
Abstract:
The measurement of the intensity of a wave propagating in a random medium results in a random signal response, the statistical properties of which are functions of the radiation wavelength and the ratio between the characteristic scale of the spatial intensity pattern and the size of the receiver aperture. In this paper, using multiscale solutions for high-frequency random propagators, we construct expressions for the integral intensity correlation measures that allow us to obtain the spectral intensity correlationcharacteristics and to analyze their variations as functions of wavelength separation and detector aperture. Numerical results are presented for a plane wave propagating in random media that are characterized by a Gaussian spectrum and by a power-law spectrum of the refractive-index fluctuations.
Related Concept Videos
Interference and Diffraction
Intensity Of Electromagnetic Waves
Difference from Background: Limit of Detection
The LOD indicates the presence or absence...
IR Spectrum Peak Intensity: Dipole Moment
Atomic Emission Spectroscopy: Interference
Phase Contrast and Differential Interference Contrast Microscopy
In-phase-contrast microscopes, interference between light directly passing through a cell and light refracted by cellular components is used to create high-contrast, high-resolution images without staining. It is the oldest and simplest type of microscope that creates an image by altering the wavelengths of light rays passing through the specimen. Altered wavelength paths are created using an annular stop in the condenser. The annular stop produces a hollow cone of...

