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Updated: Jun 9, 2026

Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents
Published on: May 28, 2014
Synthesis and structures of (dialkylsilylene)bis(phosphine)-nickel, palladium, and platinum complexes and
Chieko Watanabe1, Yuichiro Inagawa, Takeaki Iwamoto
1Department of Chemistry, Graduate School of Science, Tohoku University, Aoba-ku, Sendai 980-8578, Japan.
Abstract:
A series of dialkylsilylene-group 10 metal complexes (R(H)(2)Si)(Me(3)P)(2)M (M = Ni, Pd, Pt, R(H)(2) = 1,1,4,4-tetrakis(trimethylsilyl)butane-1,4-diyl) and novel (η(6)-arene)(dialkylsilylene)nickel complexes (η(6)-arene)(R(H)(2)Si)Ni were synthesized and characterized by NMR spectroscopy and X-ray analysis. The perpendicular geometry around the Si-M bond and the short Si-M distances of (R(H)(2)Si)(Me(3)P)(2)M complexes indicate the significant back donation from the metal to the silylene ligand.
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