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Updated: Jun 9, 2026

Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study
10:10

Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study

Published on: August 15, 2016

Effects of cogrinding with β-cyclodextrin on the solid state fentanyl

Noriko Ogawa1, Kenjirou Higashi, Hiromasa Nagase

  • 1Department of Physical Chemistry, Hoshi University, 4-41 Ebara 2-chome, Shinagawa-ku, Tokyo 142-8501, Japan. n-ogawa@hoshi.ac.jp

Journal of Pharmaceutical Sciences
|September 8, 2010
PubMed
Summary

Fentanyl and beta-cyclodextrin (β-CD) mixtures were studied. Cogrinding and humidity promote the formation of an amorphous state and hydrogen bonding, leading to a fentanyl/β-CD inclusion complex.

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