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NPY-induced inhibition of male copulatory activity is a direct behavioural effect
R Poggioli1, A V Vergoni, D Marrama
1Institute of Pharmacology, University of Modena, Italy.
Neuropeptides
|July 1, 1990
Abstract:
In adult, sexually-experienced male rats, the intracerebroventricular injection of NPY caused a dose-related inhibition of copulatory behaviour, all parameters (mount, intromission and ejaculation latencies, mount and intromission frequencies, mean inter-intromission interval, post-ejaculatory interval) being significantly worsened at the dose of 8 micrograms/rat. Since rats were deprived of food during the behavioural test, it is concluded that inhibition of sexual behaviour is a 'true', direct behavioural effect of NPY, not due to a shift towards increased feeding.