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Related Concept Videos

Tissues01:18

Tissues

Cells with similar structure and function are grouped into tissues. A group of tissues with a specialized function is called an organ. There are four main types of tissue in vertebrates: epithelial, connective, muscle, and nervous.
Tissues01:25

Tissues

Tissues are a group of cells that share a common embryonic origin. Microscopic observation reveals that the cells in a tissue share morphological features and are arranged in an orderly pattern to perform specific functions. From an evolutionary perspective, tissues appear in more complex organisms. Although there are many types of cells in the human body, they are organized into four broad categories of tissues: epithelial, connective, muscle, and nervous. Each of these categories is...
Zygotic Development And Stem Cell Formation01:10

Zygotic Development And Stem Cell Formation

The development of all multicellular organisms starts with the fusion of haploid cells called sperm and egg to form a diploid zygote. A zygote is a totipotent cell that can develop into a complete organism. The zygote undergoes cell division or cleavage to form an 8-cell mass. Until this stage, the cells are spherical, loosely attached, and remain totipotent. Totipotent cells are capable of developing both the embryonic and the extraembryonic tissues. However, as they continue to divide, they...
Morphogenesis02:19

Morphogenesis

Plant morphogenesis—the development of a plant’s form and structure—involves several overlapping developmental processes, including growth and cell differentiation. Precursor cells differentiate into specific cell types, which are organized into the tissues and organ systems that make up the functional plant.
Gastrulation01:56

Gastrulation

Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata will form...
Cells Coordinate Growth and Proliferation02:36

Cells Coordinate Growth and Proliferation

Cell size is a significant factor impacting cellular design, function, and fitness. There exists some internal coordination by which cells double their masses before division, thus, achieving homeostasis. Coordination between cell growth and proliferation depends on the checkpoints in between cell cycle phases. Loss of coordination or failure in the checkpoint mechanism can drive the cell to uncontrolled growth and loss of cellular function. Like dividing cells that coordinate cellular growth,...

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Related Experiment Video

Updated: Jun 9, 2026

Tissue Engineering: Construction of a Multicellular 3D Scaffold for the Delivery of Layered Cell Sheets
09:24

Tissue Engineering: Construction of a Multicellular 3D Scaffold for the Delivery of Layered Cell Sheets

Published on: October 3, 2014

Tissue morphogenesis: how multiple cells cooperate to generate a tissue.

Huimin Zhang1, Christelle Gally, Michel Labouesse

  • 1IGBMC, CNRS/INSERM/Université de Strasbourg, 1 rue Laurent Fries, BP. 10142, 67404 Illkirch CEDEX, France.

Current Opinion in Cell Biology
|September 9, 2010
PubMed
Summary
This summary is machine-generated.

Researchers are uncovering how cellular processes integrate for tissue morphogenesis. Novel imaging and modeling reveal principles of mechanical tension and junctional signaling in embryonic development.

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Last Updated: Jun 9, 2026

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Published on: October 3, 2014

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Published on: July 10, 2016

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08:19

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Area of Science:

  • Developmental Biology
  • Cell Biology
  • Biophysics

Background:

  • Detailed molecular understanding of cellular processes in embryonic morphogenesis is established through genetic analysis in model organisms.
  • Integration of these cellular processes across different cell groups and layers is crucial for higher-order tissue morphogenesis.

Purpose of the Study:

  • To review progress in understanding how cellular processes integrate for tissue morphogenesis.
  • To highlight novel principles and the role of cell junctions in this process.

Main Methods:

  • Review of recent scientific literature.
  • Discussion of examples from Caenorhabditis elegans and Drosophila embryos.
  • Emphasis on novel imaging methods and computational modeling.

Main Results:

  • Identification of novel principles governing tissue morphogenesis, partly based on mechanical tension.
  • Elucidation of the role of cell junctions as key signal integrators.
  • Advancements driven by new imaging techniques and modeling approaches.

Conclusions:

  • Understanding tissue morphogenesis requires integrating cellular-level processes across multicellular contexts.
  • Mechanical tension and junctional signaling are critical mechanisms.
  • Model organisms and advanced methodologies are essential for future discoveries.