Related Experiment Video

Updated: Feb 13, 2026

Demonstration of the DNA Fiber Assay for Investigating DNA Damage and Repair Dynamics Induced by Nanoparticles
13:09

Demonstration of the DNA Fiber Assay for Investigating DNA Damage and Repair Dynamics Induced by Nanoparticles

Published on: March 3, 2023

5.2K

DNA repair: a reinvigorated therapeutic target

Susan E Bates

    Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
    |September 9, 2010
    PubMed
    Abstract

    No abstract available in PubMed .

    More Related Videos

    Visualization of DNA Repair Proteins Interaction by Immunofluorescence
    07:55

    Visualization of DNA Repair Proteins Interaction by Immunofluorescence

    Published on: June 26, 2020

    11.2K
    Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy
    08:31

    Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy

    Published on: June 8, 2018

    9.7K

    Related Experiment Videos

    Last Updated: Feb 13, 2026

    Demonstration of the DNA Fiber Assay for Investigating DNA Damage and Repair Dynamics Induced by Nanoparticles
    13:09

    Demonstration of the DNA Fiber Assay for Investigating DNA Damage and Repair Dynamics Induced by Nanoparticles

    Published on: March 3, 2023

    5.2K
    Visualization of DNA Repair Proteins Interaction by Immunofluorescence
    07:55

    Visualization of DNA Repair Proteins Interaction by Immunofluorescence

    Published on: June 26, 2020

    11.2K
    Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy
    08:31

    Characterizing DNA Repair Processes at Transient and Long-lasting Double-strand DNA Breaks by Immunofluorescence Microscopy

    Published on: June 8, 2018

    9.7K

    Related Concept Videos

    Overview of DNA Repair02:25

    Overview of DNA Repair

    33.9K
    In order to be passed through generations, genomic DNA must be undamaged and error-free. However, every day, DNA in a cell undergoes several thousand to a million damaging events by natural causes and external factors. Ionizing radiation such as UV rays, free radicals produced during cellular respiration, and hydrolytic damage from metabolic reactions can alter the structure of DNA. Damages caused include single-base alteration, base dimerization, chain breaks, and cross-linkage.
    Chemically...
    33.9K
    Overview of DNA Repair02:25

    Overview of DNA Repair

    9.9K
    No description available
    9.9K
    Mismatch Repair01:36

    Mismatch Repair

    43.8K
    Overview
    43.8K
    Base-pairing and DNA Repair02:27

    Base-pairing and DNA Repair

    93.7K
    No description available
    93.7K
    Base Excision Repair01:54

    Base Excision Repair

    26.4K
    One of the common DNA damages is the chemical alteration of single bases by alkylation, oxidation, or deamination. The altered bases cause mispairing and strand breakage during replication. This type of damage causes minimal change to the DNA double helix structure and can be repaired by the base excision repair (BER) pathways. BER corrects damaged DNA sequences by removing the damaged base and restoring the original base sequence using the complementary strand as a template.
    The first step of...
    26.4K
    Nucleotide Excision Repair01:08

    Nucleotide Excision Repair

    40.9K
    Overview
    40.9K

    Articles linked to this work by shared authors, journal, and citation graph.

    Phase 2 study of azacitidine plus pembrolizumab as second-line treatment in patients with locally advanced or metastatic pancreatic ductal adenocarcinoma.

    The oncologist·2026

    International Consensus-Driven Recommendations for Patient-Reported Outcome Research Objectives in Early Phase Dose-Finding Oncology Trials: OPTIMISE-ROR.

    Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2026

    CA19-9 as a Dynamic Biomarker for Continuous Monitoring of Therapeutic Efficacy in Pancreatic Adenocarcinoma.

    Cancers·2025

    Abiraterone vs Enzalutamide Among US Veterans With Metastatic Hormone-Sensitive Prostate Cancer.

    JAMA network open·2025

    Cancer interception during treatment: using growth kinetics to create a continuous variable for assessing disease response.

    The oncologist·2025

    Combined HDAC and eIF4A inhibition: A novel epigenetic therapy for pancreatic ductal adenocarcinoma.

    Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy·2025

    Whole Genome HPV Liquid Biopsy for HPV-Associated Cancer Detection and Viral Physical State Classification.

    Clinical cancer research : an official journal of the American Association for Cancer Research·2026

    Baseline circulating and tumor γδ T cells and early circulating CD8⁺PD1⁺ expansion predict response to Atezolizumab-bevacizumab in HCC.

    Clinical cancer research : an official journal of the American Association for Cancer Research·2026

    A Phase II Trial of Pembrolizumab plus Granulocyte-Macrophage Colony-Stimulating Factor in Advanced Biliary Cancer.

    Clinical cancer research : an official journal of the American Association for Cancer Research·2026

    BRIGHTLINE-1: When a Negative Trial Reveals Two Active Therapies.

    Clinical cancer research : an official journal of the American Association for Cancer Research·2026

    EZH2 Inhibition and Myeloid Risk: A Feature of On-Target Biology.

    Clinical cancer research : an official journal of the American Association for Cancer Research·2026

    The pan-tumor landscape, allelic status, and genomic complexity of SMARCA4 alterations.

    Clinical cancer research : an official journal of the American Association for Cancer Research·2026

    A Retrospective Evaluation of the Look-Back Technique for Improving Early Perioperative Outcomes in Unilateral Laminectomy Bilateral Decompression With Unilateral Biportal Endoscopy.

    International journal of spine surgery·2026

    Isorhoifolin regulates S1PR3-CK2-GSK3β axis and promotes neurite regrowth and functional recovery after traumatic brain injury.

    Phytomedicine : international journal of phytotherapy and phytopharmacology·2026

    Natural history and clinical outcomes of de novo functional tricuspid regurgitation after the Ross procedure.

    JTCVS open·2026

    Efficacy of Integrating the Interactive Virtual Device (REAtouch®) into HABIT-ILE for Children with Bilateral Cerebral Palsy: A Randomized Controlled Non-Inferiority Trial.

    Neurorehabilitation and neural repair·2026

    Integrated predictors of outcome in vertebrobasilar artery occlusion treated With endovascular therapy.

    Frontiers in surgery·2026

    Residual bone mass after TLIF treated by TELD under local anesthesia: a case report.

    Frontiers in surgery·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us