Photodynamic therapy for cosmetic uses on the skin: an update 2010

The utilization of photodynamic therapy (PDT) in the United States has reached an all-time high with many clinicians utilizing this form of therapy for a myriad of dermatologic disorders. World-wide, PDT is now being introduced to a wider audience. The purpose of this manuscript is to review PDT, from its history to it current uses and indications, and to expand upon its proper use and after care, to minimize any potential adverse events, and to make PDT treatments useful and effective for all of our patients. Two photosensitizers are now routinely available in the US and we will review both of these sensitizers, their FDA and off-label uses, and their affects on the skin and how they have made a positive effect in dermatology.