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Updated: Jun 9, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
Ileocecal intussusception in the adult population: case series of two patients
Deena Ibrahim1, Nina P Patel, Malkeet Gupta
1University of California, Irvine, Department of Emergency Medicine, Irvine, CA.
Insights
Adult intussusception, often caused by a lead point like surgical scars or tumors, requires prompt diagnosis and surgical intervention. This condition can mimic other abdominal issues, necessitating a broad differential diagnosis for emergency physicians.
Area of Science:
- Gastroenterology
- Surgical Pathology
Background:
- Intussusception is rare in adults, unlike in children.
- In adults, it often indicates an underlying pathological process.
- Potential complications include bowel obstruction, ischemia, and necrosis.
Purpose of the Study:
- To highlight the varied etiologies of adult intussusception.
- To emphasize the importance of considering intussusception in adult abdominal pain differentials.
- To present cases illustrating common lead points in adult intussusception.
Main Methods:
- Case report presentation of two adult patients with intussusception.
- Review of diagnostic imaging and surgical findings.
- Analysis of etiologies including iatrogenic and neoplastic causes.
Main Results:
- A 21-year-old female with ileocecal intussusception secondary to an appendectomy scar.
- A 66-year-old male with ileocolic intussusception caused by colon adenocarcinoma.
- Both cases required surgical intervention.
Conclusions:
- Adult intussusception typically involves a lead point, such as adhesions, scars, or tumors.
- It can present with symptoms mimicking other abdominal pathologies, including bowel obstruction.
- Emergency physicians should include intussusception in the differential diagnosis for adult abdominal pain.
Background:
Intussusception is a condition found primarily in the pediatric population. In the adult population, however, intussusception is usually due to a pathological process, with a higher risk of bowel obstruction, vascular compromise, inflammatory changes, ischemia, and necrosis. Radiographic and sonographic evidence can aid in the diagnosis. Surgical intervention involving resection of affected bowel is the standard of care in adult cases of intussusception.
Case Reports:
We present the case of a 21-year-old female who presented to the Emergency Department with diffuse cramping abdominal pain and distention. Workup revealed ileocecal intussusception, with a prior appendectomy scar serving as the lead point discovered during exploratory laparotomy. We also present the case of a 66-year-old male, who presented with one week of intermittent lower abdominal pain associated with several episodes of nausea and vomiting. Workup revealed ileocolic intussusception secondary to adenocarcinoma of the right colon, confirmed upon exploratory laparotomy with subsequent right hemicolectomy.
Conclusion:
In the adult population, intussusception is usually caused by a lead point, with subsequent telescoping of one part of the bowel into an adjacent segment. While intussusception can occur in any part of the bowel, it usually occurs between a freely moving segment and either a retroperitoneal or an adhesion-fixed segment. The etiology may be associated with pathological processes such as carcinoma or iatrogenic causes, such as scars or adhesions from prior surgeries. The cases presented here demonstrate important etiologies of abdominal pain in adult patients. Along with gynecological etiologies of lower quadrant abdominal pain in female patients, it is important for the emergency physician to expand the differential diagnosis to include other causes, such as intussusceptions, especially given the symptoms that could be associated with bowel obstruction.
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