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Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

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Creation and Maintenance of a Living Biobank - How We Do It
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Tissue banking for research: connecting the disconnected.

Geraldine Thomas1

  • 1Human Cancer Studies Group, Department of Surgery and Cancer, Hammersmith Hospital, Du Cane Road, London, UK. geraldine.thomas@imperial.ac.uk

Cell and Tissue Banking
|September 9, 2010
PubMed
Summary

Achieving personalized medicine requires extensive human tissue samples. Enhancing National Health Service (NHS) infrastructure and public support is crucial for acquiring these samples for research.

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Area of Science:

  • Biomedical research
  • Translational medicine
  • Genomics

Background:

  • Personalized medicine aims to tailor treatments to individual patients.
  • Significant variations in human physiology and disease necessitate large-scale tissue sample access.
  • Current infrastructure presents challenges in connecting National Health Service (NHS) resources with tissue-based research.

Purpose of the Study:

  • To highlight the critical need for a robust translational platform for personalized medicine.
  • To identify key requirements for leveraging NHS infrastructure for tissue sample acquisition.
  • To address the disconnection between clinical practice and research for improved patient outcomes.

Main Methods:

  • Analysis of current challenges in personalized medicine research.
  • Identification of the role of the NHS in sample acquisition.
  • Conceptual framework for a translational platform.

Main Results:

  • Access to large-scale human tissue samples is essential for personalized medicine.
  • Public consent and increased NHS support (manpower, administration) are vital.
  • A disconnect exists between NHS and tissue research, hindering progress.

Conclusions:

  • Bridging the gap between the NHS and tissue research is paramount.
  • Establishing a translational platform will accelerate the development of tailored treatments.
  • Optimizing sample acquisition pathways will enable effective disease cures with minimal side effects.