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Related Concept Videos

Pulmonary Embolism I: Introduction01:29

Pulmonary Embolism I: Introduction

Pulmonary embolism (PE) occurs when a thrombus, fat or air embolus, amniotic fluid, or tumor tissue blocks one or more pulmonary arteries. These blockages originate in the venous system or the right side of the heart.EtiologyPE primarily arises from deep vein thrombosis (DVT) and other hypercoagulable states, such as inherited thrombophilias. Additional etiological factors include venous stasis, commonly seen in obesity, and endothelial injury from surgery and trauma. Less common causes include...
Pulmonary Embolism I: Introduction01:19

Pulmonary Embolism I: Introduction

A blood clot, or thrombus, is a semi-solid mass composed of fibrin, platelets, and red blood cells. When it forms within a vessel, it can obstruct blood flow, known as thrombosis. If part of the clot detaches, it becomes an embolus that can travel and block distant vessels. When this occurs in the pulmonary arteries, it causes a condition known as pulmonary embolism (PE).Origin and ImpactMost often, the embolus originates from a thrombus in the deep veins of the lower limbs, a condition called...
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
Pulmonary Embolism III: Nursing Management01:27

Pulmonary Embolism III: Nursing Management

A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
Acute Respiratory Failure-I01:21

Acute Respiratory Failure-I

Acute respiratory failure is a condition characterized by the inability of the lungs to perform their primary function: gas exchange. This failure leads to insufficient oxygen levels (hypoxemia) in the blood, elevated carbon dioxide levels (hypercapnia), or both, causing critical impairment in organ function.
Definition: It is defined by specific criteria based on blood gas measurements. Hypoxemia happens when the partial pressure of oxygen (PaO2) falls below 60 mmHg. At the same time,...

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Related Experiment Video

Updated: Jun 9, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
07:44

A Porcine Model of Acute Autologous Pulmonary Embolism

Published on: September 6, 2024

[Acute pulmonary embolism].

S Braun1, J Beyer-Westendorf, I Platzek

  • 1Medizinische Klinik I - Pneumologie, Universitätsklinikum Carl-Gustav-Carus, Dresden, Germany. Silke.Braun@uniklinikum-dresden.de

Deutsche Medizinische Wochenschrift (1946)
|September 9, 2010
PubMed
Summary
This summary is machine-generated.

Acute pulmonary embolism (APE) requires prompt diagnosis and risk stratification. High-risk APE necessitates immediate intervention, while stable patients benefit from sequential workup and anticoagulation.

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Last Updated: Jun 9, 2026

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Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots
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Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots

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Area of Science:

  • Cardiology
  • Pulmonology
  • Emergency Medicine

Background:

  • Acute pulmonary embolism (APE) presents with diverse clinical symptoms, from asymptomatic cases to sudden death.
  • Prompt diagnosis of APE is critical due to its potentially fatal nature.

Purpose of the Study:

  • To outline diagnostic and therapeutic algorithms for acute pulmonary embolism.
  • To differentiate management strategies based on hemodynamic stability.

Main Methods:

  • Stratification of patients into high-risk and non-high-risk APE based on shock or hypotension.
  • Utilizing multidetector CT or echocardiography for immediate diagnosis in high-risk cases.
  • Recommending sequential diagnostic workup and anticoagulation for hemodynamically stable patients.

Main Results:

  • Hemodynamic instability dictates immediate diagnostic and therapeutic pathways for APE.
  • High-risk APE management involves rapid diagnosis and intervention (thrombolysis or embolectomy).
  • Non-high-risk APE is managed with a sequential diagnostic approach and prompt anticoagulation.

Conclusions:

  • Prompt risk stratification is essential for effective acute pulmonary embolism management.
  • Tailored diagnostic and therapeutic strategies based on hemodynamic status improve patient outcomes.
  • Timely intervention in high-risk APE and anticoagulation in stable patients are crucial.