A spatial dirichlet process mixture model for clustering population genetics data
Related Experiment Video
Updated: May 8, 2026

A Novel Bayesian Change-point Algorithm for Genome-wide Analysis of Diverse ChIPseq Data Types
Published on: December 10, 2012
Brian J Reich1, Howard D Bondell
1Department of Statistics, North Carolina State University, Raleigh, North Carolina 27695, USA. reich@stat.ncsu.edu
Abstract:
Identifying homogeneous groups of individuals is an important problem in population genetics. Recently, several methods have been proposed that exploit spatial information to improve clustering algorithms. In this article, we develop a Bayesian clustering algorithm based on the Dirichlet process prior that uses both genetic and spatial information to classify individuals into homogeneous clusters for further study. We study the performance of our method using a simulation study and use our model to cluster wolverines in Western Montana using microsatellite data.
Related Concept Videos
What is Population Genetics?
Mutation, Gene Flow, and Genetic Drift
Cluster Sampling Method
To choose a cluster sample, divide the population into clusters (groups) and then randomly select some of the clusters. All the members from these clusters are in the cluster sample. For example, if you randomly sample four departments from your...
Distributions to Estimate Population Parameter
Mechanistic Models: Compartment Models in Algorithms for Numerical Problem Solving
In individual population analyses, different algorithms are employed, such as Cauchy's method, which uses a...
Model Approaches for Pharmacokinetic Data: Distributed Parameter Models
The distributed parameter models are specifically designed to account for variations and differences in some drug classes. This model is particularly useful for assessing regional concentrations of anticancer or...

