Related Experiment Video

Updated: Jun 9, 2026

A Novel High-Throughput Ex Vivo Ovine Skin Wound Model for Testing Emerging Antibiotics
08:30

A Novel High-Throughput Ex Vivo Ovine Skin Wound Model for Testing Emerging Antibiotics

Published on: September 16, 2022

Current concepts in the management of bacterial skin infections in children

Aparna Palit1, Arun C Inamadar

  • 1Department of Dermatology, Venereology and Leprosy, SBMP Medical College, Hospital and Research Center, BLDE University, Bijapur, Karnataka, India.

Indian Journal of Dermatology, Venereology and Leprology
|September 10, 2010
PubMed

Insights

Pediatric bacterial skin infections, from mild to severe, are challenging due to rising antibiotic resistance. Effective management requires understanding current resistance patterns for common bacteria like Staphylococcus aureus and Streptococcus.

Area of Science:

  • Pediatric dermatology
  • Infectious diseases
  • Microbiology

Background:

  • Bacterial skin infections in children present a spectrum from superficial folliculitis to necrotizing fasciitis.
  • Common pathogens include Staphylococcus aureus and Streptococcus, with Gram-negative organisms also implicated.
  • Despite varying severity, prompt treatment is crucial to prevent long-term morbidity.

Purpose of the Study:

  • To review current antibacterial resistance patterns in pediatric skin and soft tissue infections.
  • To discuss challenges in managing these infections in children.
  • To highlight the impact of antimicrobial resistance on treatment efficacy.

Main Methods:

  • Literature review of current research on pediatric bacterial skin infections.
  • Analysis of antimicrobial resistance patterns.
  • Discussion of clinical management strategies and challenges.

Main Results:

  • Increasing prevalence of antibiotic-resistant strains of Staphylococcus aureus and Streptococcus.
  • Growing difficulty in treating common bacterial skin infections in children.
  • Need for updated treatment guidelines based on local resistance data.

Conclusions:

  • Antibiotic resistance poses a significant threat to the effective treatment of pediatric bacterial skin infections.
  • Understanding local resistance patterns is essential for appropriate therapeutic selection.
  • Further research and surveillance are needed to combat antimicrobial resistance in pediatric dermatology.

More Related Videos

In Vivo Investigation of Antimicrobial Blue Light Therapy for Multidrug-resistant Acinetobacter baumannii Burn Infections Using Bioluminescence Imaging09:29

In Vivo Investigation of Antimicrobial Blue Light Therapy for Multidrug-resistant Acinetobacter baumannii Burn Infections Using Bioluminescence Imaging

Published on: April 28, 2017

Related Concept Videos

Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Hand hygiene01:23

Hand hygiene

Asepsis is the practice of preventing or breaking the chain of infection. The nurse employs aseptic techniques to prevent the spread of microorganisms and reduce the risk of diseases. Hand hygiene is the cornerstone of aseptic techniques and is classified into medical and surgical asepsis. Medical asepsis includes hand hygiene and the use of gloves. Surgical asepsis, or the sterile technique, refers to practices that render and keep objects and areas free of microorganisms.
Hand washing...