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Updated: Jun 9, 2026
05:07
Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
[A bleeding ileal ulcer associated with Sweet's syndrome]
Jun Takada1, Hiroshi Araki, Fumito Onogi
1Department of Gastroenterology, Gifu University, Gifu, Japan. jun-t@nishimino.gfkosei.or.jp
Nihon Shokakibyo Gakkai Zasshi = the Japanese Journal of Gastro-Enterology
|September 10, 2010
Summary
A rare case of Sweet's syndrome complicated by bleeding ileal ulcers was successfully treated with prednisolone. This treatment resolved both the skin lesions and gastrointestinal bleeding, with no recurrence after medication cessation.
Area of Science:
- Dermatology
- Gastroenterology
Background:
- Sweet's syndrome is an acute febrile neutrophilic dermatosis.
- Gastrointestinal manifestations are rare but can be severe.
Observation:
- A 76-year-old woman presented with Sweet's syndrome and developed hematochezia.
- Endoscopy revealed multiple punched-out ulcers in the terminal ileum with active bleeding.
Findings:
- Endoscopic hemoclip application achieved hemostasis for a pulsating hemorrhage.
- Oral prednisolone (PSL) treatment led to the resolution of both ileal ulcers and skin erythema.
Implications:
- This case highlights the importance of considering gastrointestinal involvement in Sweet's syndrome.
- Systemic corticosteroid therapy, such as PSL, can effectively manage associated gastrointestinal ulcers and bleeding.
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