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Updated: Jun 9, 2026

Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
Primary osteolytic intraosseous meningioma of the frontal bone
Adem Yilmaz1, Murat Musluman, Yunus Aydin
1Department of Neurosurgery, Sişli Etfal Education and Research Hospital, Sişli, Istanbul 34077, Turkey. ademyilmaz70@yahoo.com
Abstract:
Almost 1-2% of meningiomas are lesions described as ectopic or extradural meningiomas. Primary intraosseous meningiomas are a rare form of intra-bone tumours that account for approximately 67% of extradural meningiomas. A 41-year-old male patient presented with a headache and a bulge at the right frontal region. Cranial computed tomography displayed a hyperostotic lesion. Magnetic resonance imaging showed enhancement of the bone lesion after injection of gadolinium. A burr hole was drilled at the thickest section of the lesion, and pathological examination of the bone dust extracted from this site was performed. The pathological study indicated the presence of a meningioma. Right frontal craniectomy was performed and the hyperostotic bone was resected. No invasion was observed at the dura. A calvarial defect was reconstructed during the same session with methyl methacrylate cranioplasty.
Insights
This study reports a rare case of primary intraosseous meningioma, an extradural meningioma presenting as a hyperostotic bone lesion. Surgical resection and cranioplasty were successfully performed.
Area of Science:
- Neurosurgery
- Oncology
- Pathology
Background:
- Ectopic or extradural meningiomas constitute 1-2% of all meningiomas.
- Primary intraosseous meningiomas represent approximately 67% of extradural meningiomas, making them rare intra-bone tumors.
Observation:
- A 41-year-old male presented with headache and a right frontal bulge.
- Cranial CT revealed a hyperostotic lesion, and MRI showed gadolinium enhancement.
- Pathological examination of bone dust confirmed meningioma.
Findings:
- Surgical resection of the hyperostotic bone lesion was performed.
- No dural invasion was observed.
- Methyl methacrylate cranioplasty reconstructed the calvarial defect.
Implications:
- This case highlights the importance of considering primary intraosseous meningioma in the differential diagnosis of hyperostotic cranial lesions.
- Successful surgical management and reconstruction were achieved.
- Further research into the pathogenesis and optimal treatment of these rare tumors is warranted.
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