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Published on: January 7, 2021
Fetal ocular measurements by MRI.
Xiao Bing Li1, Gregor Kasprian, Jacqueline C Hodge
1Department of Radiology, Nanjing Medical University affiliated Suzhou Hospital, Suzhou Municipal Hospital, Suzhou, China. mrisus@gmail.com
Prenatal Diagnosis
|September 10, 2010
Summary
Fetal magnetic resonance imaging (MRI) provides ocular measurement ranges for normal and growth-restricted fetuses. These findings aid in detecting fetal ocular anomalies and understanding their impact on vision.
Area of Science:
- Medical Imaging
- Fetal Development
- Ophthalmology
Background:
- Accurate fetal ocular measurements are crucial for assessing development and identifying potential anomalies.
- Normative data for fetal ocular parameters across gestational ages is essential for clinical interpretation.
Purpose of the Study:
- To establish normative ranges for fetal ocular measurements using magnetic resonance imaging (MRI) across different gestational ages (GA).
- To compare ocular measurements between normal fetuses and those with intrauterine growth restriction (IUGR).
Main Methods:
- Fetal MRI was performed on 298 pregnant women between 18 and 39 weeks of gestation.
- Key ocular measurements included binocular distance (BOD), interocular distance (IOD), transverse ocular diameter (OD), and anterior-posterior (AP) OD.
- Quadratic models were used for curve estimation, and ocular measurements were compared between normal and IUGR fetuses.
Main Results:
- The fetal eye was characterized as an ellipsoid with significantly longer OD than AP.
- Quadratic models effectively predicted the growth of fetal BOD, IOD, OD, and AP.
- Fetuses with IUGR exhibited significantly different ocular measurements (BOD, IOD, OD, AP) compared to normal fetuses.
Conclusions:
- Fetal MRI is a viable tool for assessing fetal ocular growth.
- The normative data presented can aid in the detection of fetal ocular anomalies.
- Reduced ocular size in IUGR fetuses suggests potential impacts on postnatal vision.
