Related Experiment Videos
[Preparation of monodesethylamodiaquine from human urine]
S Ménager1, O Lafont, P Chrétien
1Groupe de Pharmacochimie, Faculté de Médecine, Saint-Etienne-du-Rouvray.
Annales Pharmaceutiques Francaises
|January 1, 1990
Abstract:
60 mg of monodesethylamodiaquine, the active metabolite of amodiaquine were prepared by extraction from human urine, at pH 11-12, using ethyl acetate. The purification was carried out by medium pressure liquid chromatography. The identity and the purity of the compound were checked by thin layer chromatography, 1H nuclear magnetic resonance and mass spectrometry.