Newborns from in vitro fertilization conceived pregnancies

Area of Science:

• Reproductive Medicine
• Neonatology
• Public Health

Background:

• Infertility is a growing global concern, significantly impacting Serbia's demographic trends with one-third of couples childless.
• Health issues contribute to infertility in half of childless couples in Serbia.
• In vitro fertilization (IVF) is a common treatment for infertility.

Purpose of the Study:

• To analyze the morbidity and mortality of newborns conceived via IVF.
• To identify critical factors influencing the health outcomes of these premature newborns in intensive care.

Main Methods:

• Retrospective analysis of 2 years of data from Neonatal Intensive Care Units (NICUs) in Novi Sad and Belgrade, Serbia.
• Inclusion of newborns conceived via IVF requiring intensive care treatment.
• Evaluation of factors such as prematurity, low birth weight, perinatal asphyxia, and systemic hypotension.

Main Results:

• A significant number of IVF-conceived newborns require NICU admission.
• Prematurity, low birth weight, and perinatal asphyxia are major contributors to morbidity.
• Systemic hypotension presents a critical challenge, necessitating early prevention and treatment.

Conclusions:

• IVF-conceived newborns face significant morbidity risks, particularly related to prematurity and low birth weight.
• Effective management of systemic hypotension is crucial for improving outcomes in these vulnerable infants.
• Further research is needed to optimize care for IVF-conceived neonates.