Related Experiment Video
Updated: Jun 9, 2026

12:03
A Method for Tracking the Time Evolution of Steady-State Evoked Potentials
Published on: May 25, 2019
Predicting hearing thresholds and occupational hearing loss with multiple-frequency auditory steady-state responses.
Ruey-Fen Hsu1, Chi-Kung Ho, Sheng-Nan Lu
1Departments of Otolaryngology and Occupational Medicine, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Summary
Multiple-frequency auditory steady-state responses (Mf-ASSRs) show strong correlation with pure-tone thresholds for assessing hearing loss. However, Mf-ASSR accuracy may be lower in noise-induced hearing loss cases.
Area of Science:
- Audiology
- Occupational Health
- Otoacoustic Emissions
Background:
- Work-related noise exposure can cause sensorineural hearing loss (SNHL).
- Objective hearing assessment is crucial for medicolegal arbitration of noise-induced hearing loss (NIHL).
- Multiple-frequency auditory steady-state responses (Mf-ASSRs) offer an objective measure of hearing thresholds.
Purpose of the Study:
- To investigate the accuracy of Mf-ASSRs in individuals with SNHL, comparing those with and without occupational noise exposure.
- To evaluate Mf-ASSRs as a tool for medicolegal assessment of NIHL.
- To develop a predictive equation for hearing thresholds using Mf-ASSRs.
Main Methods:
- A cross-sectional study was conducted at a tertiary referral medical center.
- Pure-tone audiometry and Mf-ASSRs were performed on 88 subjects: 34 with NIHL, 36 with SNHL without noise exposure, and 18 normal controls.
- Inter- and intragroup comparisons were made, and multiple linear regression analysis was used to derive a predictive equation.
Main Results:
- A strong correlation was found between Mf-ASSRs and pure-tone thresholds (PTTs) across all subjects (r = .77–.94).
- The difference between Mf-ASSRs and PTTs was significantly greater in the NIHL group compared to the non-noise-induced SNHL group (p < .001).
- A predictive equation was derived to estimate hearing thresholds.
Conclusions:
- Mf-ASSR is a promising objective tool for hearing threshold evaluation.
- The predictive value of Mf-ASSR may be reduced in cases of occupational hearing loss.
- Mf-ASSR can aid in detecting auditory pathway injury from noise exposure and assist in medicolegal evaluations.

