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Epilepsy with occipital features in children: factors predicting seizure outcome and neuroimaging abnormalities

Dewi Schrader1, Ruchika Shukla, Renee Gatrill

  • 1Division of Pediatric Neurology, Department of Pediatrics, University of British Columbia and British Columbia's Children's Hospital, 4480 Oak Street, Vancouver, BC, V6H 3V4, Canada.

European Journal of Paediatric Neurology : EJPN : Official Journal of the European Paediatric Neurology Society
|September 11, 2010
PubMed

Insights

In children with occipital epilepsy, an early age of seizure onset and abnormal neurological exams strongly predict abnormal MR imaging findings. Seizure outcomes were not reliably predicted by these factors.

Area of Science:

  • Pediatric Neurology
  • Epileptology
  • Neuroimaging

Background:

  • Occipital epilepsy is a significant neurological condition in children.
  • Identifying predictors of neuroimaging abnormalities and seizure outcomes is crucial for management.

Purpose of the Study:

  • To identify clinical and electroencephalogram (EEG) features predicting Magnetic Resonance (MR) imaging abnormalities in pediatric occipital epilepsy.
  • To determine predictors of seizure outcome in this population.

Main Methods:

  • Retrospective analysis of a pediatric epilepsy database.
  • Evaluation of clinical and EEG data from patients with occipital lobe involvement.
  • Correlation of features with MR imaging results and seizure outcomes.

Main Results:

  • Early age of seizure onset and abnormal neurological examinations were significant predictors of abnormal MR imaging.
  • Thirty-three patients had normal neurological development and neuroimaging; 22 met criteria for idiopathic occipital syndromes.
  • No variables strongly predicted seizure outcome.

Conclusions:

  • Early seizure onset and abnormal neurological exams are key indicators of MR imaging abnormalities in pediatric occipital epilepsy.
  • Further research may be needed to identify predictors of seizure outcome.
Abstract

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